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New treatment option for Brachial Plexus Blockade
Official title Dose-Finding Study: MEV90 for Local Anesthetic in Interscalene Block for Supraclavicular Nerves Block
ClinicalTrials.gov ID: NCT07338916
What this study is testing
What is Ultrasound-Guided Interscalene Block with Bupivacaine?
Ultrasound-Guided Interscalene Block with Bupivacaine is an investigational medicine, given as an injectable medicine, being studied as a potential treatment for brachial plexus blockade.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study aims to determine the minimum effective volume (MEV90) of local anesthetic required to achieve sensory block of the supraclavicular nerves when performing a single-shot ultrasound-guided interscalene brachial plexus block (ISB). These nerves provide sensation to the skin over the clavicle and shoulder and are often involved in surgeries such as shoulder arthroscopy and clavicle repair.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age ≥ 18 years
- ASA physical status I to III
- Body Mass Index (BMI) between 18 and 35 kg/m²
- Weight ≥ 50 kg
- Scheduled for shoulder arthroscopy requiring an interscalene brachial plexus block for analgesia
You likely can't join if
- Inability to provide informed consent
- Coagulopathy (platelet count ≤100,000; INR ≥1.4)
- Significant pulmonary disease (restrictive or obstructive)
- Renal insufficiency (creatinine ≥1.2 mg/dL)
- Hepatic insufficiency (transaminases ≥100 U/L)
- Allergy to local anesthetics
See the full eligibility criteria
- Age ≥ 18 years
- ASA physical status I to III
- Body Mass Index (BMI) between 18 and 35 kg/m²
- Weight ≥ 50 kg
- Scheduled for shoulder arthroscopy requiring an interscalene brachial plexus block for analgesia
- Able to provide informed consent
- Inability to provide informed consent
- Coagulopathy (platelet count ≤100,000; INR ≥1.4)
- Significant pulmonary disease (restrictive or obstructive)
- Renal insufficiency (creatinine ≥1.2 mg/dL)
- Hepatic insufficiency (transaminases ≥100 U/L)
- Allergy to local anesthetics
- Pregnancy
- Pre-existing neuropathy
- Previous surgery in ipsilateral cervical or supraclavicular region
- Contralateral hemidiaphragmatic paralysis or vocal cord paralysis
The study team makes the final eligibility decision.
Where it's taking place
- Providencia, Chile
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Providencia, Chile. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.