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Official title Fungal Empyema Thoracis
ClinicalTrials.gov ID: NCT07337993
What this study is testing
- What it's testing
- Background: Fungal empyema thoracis is a rare but life-threatening pleural infection caused by fungal organisms such as Aspergillus and Candida species. It typically occurs in immunocompromised or debilitated patients and carries a high mortality rate.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Adults
You may be able to join if
- All age patients with confirmed fungal empyema thoracis.
- Patients with adequate pleural drainage through an intercostal chest tube.
- Patients receiving systemic antifungal therapy.
- Patients either:
- scheduled for surgical decortication but undergoing lavage as a preoperative adjunct, or
You likely can't join if
- Bacterial empyema without fungal growth.
- Known hypersensitivity to anti-fungals.
- Severe hepatic impairment (Child-Pugh class C) contraindicating voriconazole.
- Pregnancy or lactation.
- Refusal to participate.
See the full eligibility criteria
- All age patients with confirmed fungal empyema thoracis.
- Patients with adequate pleural drainage through an intercostal chest tube.
- Patients receiving systemic antifungal therapy.
- Patients either:
- scheduled for surgical decortication but undergoing lavage as a preoperative adjunct, or
- considered unfit for surgery and managed conservatively.
- Bacterial empyema without fungal growth.
- Known hypersensitivity to anti-fungals.
- Severe hepatic impairment (Child-Pugh class C) contraindicating voriconazole.
- Pregnancy or lactation.
- Refusal to participate.
The study team makes the final eligibility decision.
Where it's taking place
- Lahore, Punjab Province, Pakistan
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, not specified. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Lahore, Punjab Province, Pakistan. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.