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New treatment option for Abdominal Surgery
Official title External Oblique Intercostal Plane Block for Postoperative Analgesia After Major Upper Abdominal Surgery
ClinicalTrials.gov ID: NCT07331441
What this study is testing
- What it's testing
- Postoperative pain after laparoscopic major upper abdominal surgery (e.g., gastric, hepatic, gallbladder, pancreatic surgery) is often severe, and inadequate analgesia may lead to increased opioid use, opioid dependence, and poor functional recovery. Current analgesic techniques such as neuraxial block have safety concerns (e.g., hypotension, neurological injury), while transversus abdominis plane (TAP) block is ineffective for blocking the lateral cutaneous branches of intercostal nerves in the upper abdomen.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 85
You may be able to join if
- Obtain written informed consent from participants or their legal representatives
- Age between 18 and 85 years
- American Society of Anesthesiologists (ASA) physical status classification I-III
- Scheduled for elective laparoscopic major upper abdominal surgery (e.g., gastric, hepatic, gallbladder, pancreatic surgery)
- Expected surgical duration ≥ 2 hours
You likely can't join if
- Hepatic disease (liver enzyme levels ≥ 2× the upper limit of normal)
- Renal disease (serum creatinine levels ≥ 2× the upper limit of normal)
- Allergy to local anesthetics or known study-related drugs
- Pregnancy or lactation
- Low surgical incision site (not involving the upper abdominal wall innervated by T6-T10 nerves)
- Coagulopathy or current use of anticoagulant medications
See the full eligibility criteria
- Obtain written informed consent from participants or their legal representatives
- Age between 18 and 85 years
- American Society of Anesthesiologists (ASA) physical status classification I-III
- Scheduled for elective laparoscopic major upper abdominal surgery (e.g., gastric, hepatic, gallbladder, pancreatic surgery)
- Expected surgical duration ≥ 2 hours
- Ability to use the intravenous patient-controlled analgesia (IV PCA) system
- Hepatic disease (liver enzyme levels ≥ 2× the upper limit of normal)
- Renal disease (serum creatinine levels ≥ 2× the upper limit of normal)
- Allergy to local anesthetics or known study-related drugs
- Pregnancy or lactation
- Low surgical incision site (not involving the upper abdominal wall innervated by T6-T10 nerves)
- Coagulopathy or current use of anticoagulant medications
- Opioid use for more than 2 weeks in the past 6 months
The study team makes the final eligibility decision.
Where it's taking place
- Shanghai, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 85 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Shanghai, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.