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New treatment option for Prevention of White Spot Lesions in Patients Undergoing Orthodontic...
Official title Effect of Hydroxyapatite Toothpaste and Mouthwash in Preventing White Spot Lesions During Orthodontic Treatment
ClinicalTrials.gov ID: NCT07325643
What this study is testing
- What it's testing
- This study aims to evaluate the effect of hydroxyapatite-containing toothpaste and mouthwash in preventing white spot lesions in patients undergoing orthodontic treatment. Participants: 75 patients will be divided into three groups: Group A: Participants will brush their teeth three times a day using hydroxyapatite toothpaste and rinse twice a day with a placebo mouthwash.
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Adults. Healthy volunteers may be eligible.
You may be able to join if
- All included participants will be drawn from those who will receive comprehensive orthodontic treatment and fulfill the following
- Complete permanent dentition up to the first premolar, with no intended extractions in orthodontic treatment plan.
- Good overall health.
- Good oral hygiene: full-mouth plaque score \< 20%.
- No bleeding upon probing after 30 seconds.
You likely can't join if
- 1\. History of previous orthodontic treatment. 2. Bleaching or topical fluoridation within the last six months. 3. Severely rotated any of the study...
- 4\. Visible signs of caries, fluorosis, hypocalcification, or other developmental defects. 5. Restoration on the labial surface of the study teeth...
- 7\. Craniofacial anomalies and clefts.
See the full eligibility criteria
- All included participants will be drawn from those who will receive comprehensive orthodontic treatment and fulfill the following
- Complete permanent dentition up to the first premolar, with no intended extractions in orthodontic treatment plan.
- Good overall health.
- Good oral hygiene: full-mouth plaque score \< 20%.
- No bleeding upon probing after 30 seconds.
- Discontinuous band of plaque at the gingival margin.
- Normal stimulated salivary flow rate.
- Normal buffer capacity (final pH between 6.0 and 7.0) -
- 1\. History of previous orthodontic treatment. 2. Bleaching or topical fluoridation within the last six months. 3. Severely rotated any of the study teeth (limiting the appearance of facial surfaces).
- 4\. Visible signs of caries, fluorosis, hypocalcification, or other developmental defects. 5. Restoration on the labial surface of the study teeth. 6. Systemic or endocrine conditions (e.g., cardiac pacemakers, diabetes...
- 7\. Craniofacial anomalies and clefts.
The study team makes the final eligibility decision.
Where it's taking place
- Baghdad, Iraq
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, not specified. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Baghdad, Iraq. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.