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New treatment option for Myofascial Pain
Official title Multi-modal Imaging of Myofascial Pain - Phase 2
ClinicalTrials.gov ID: NCT07322445
What this study is testing
What is 50/50 Mixture of Lidocaine 1% injection + Bupivacaine 0.25% Injectable Solution?
50/50 Mixture of Lidocaine 1% injection + Bupivacaine 0.25% Injectable Solution is an investigational medicine, given as an injectable medicine, being studied as a potential treatment for myofascial pain.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The goal of this study is to evaluate imaging biomarkers for quantitative assessments of myofascial pain and determine their ability to monitor treatment response and predict clinical outcomes.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- Adults between the ages of 18 and 80 years old.
- History of spontaneous (non-provoked) pain in the neck and/or shoulder region lasting at least 3 months. Neck and/or shoulder pain, unilateral or...
- Presence of a palpable myofascial trigger point (MTrP) in one or both upper trapezius muscles.
- The participant has a Numeric Pain Rating Scale of 4/10 or more in the last one week, and the pain is reproducible by palpating the trigger point.
- Pain localized to the area of the trigger point that is reproduced or worsened upon palpation.
You likely can't join if
- Age \ 80 years old.
- Acute cervical spine pathology, trauma (e.g. whiplash) or cervical radiculopathy
- History of surgery involving the head, neck, or shoulder girdle.
- Presence of neuromuscular pathologies or inflammatory muscle diseases (e.g. dermatomyositis)
- Systemic disease with diffuse body pain (e.g. system lupus erythematosus)
- Peripheral neuropathy
See the full eligibility criteria
- Adults between the ages of 18 and 80 years old.
- History of spontaneous (non-provoked) pain in the neck and/or shoulder region lasting at least 3 months. Neck and/or shoulder pain, unilateral or bilateral.
- Presence of a palpable myofascial trigger point (MTrP) in one or both upper trapezius muscles.
- The participant has a Numeric Pain Rating Scale of 4/10 or more in the last one week, and the pain is reproducible by palpating the trigger point.
- Pain localized to the area of the trigger point that is reproduced or worsened upon palpation.
- Radiation of pain to the head, neck, or face with palpation is allowed but not required.
- Age \ 80 years old.
- Acute cervical spine pathology, trauma (e.g. whiplash) or cervical radiculopathy
- History of surgery involving the head, neck, or shoulder girdle.
- Presence of neuromuscular pathologies or inflammatory muscle diseases (e.g. dermatomyositis)
- Systemic disease with diffuse body pain (e.g. system lupus erythematosus)
- Peripheral neuropathy
- Cancer-related pain
- Pregnancy, coagulopathy or other bleeding disorder, fever, general/local infection at the pain site, substance abuse, or any other diseases that may account for signs and symptoms mimicking myofascial pain.
- Contraindication to MRI
- Chronic fatigue syndrome, fibromyalgia, or chronic Lyme disease.
- Use of acupuncture or changes in pain medications within 6 weeks of enrollment.
- Receipt of Botox injection to the neck/shoulder region within the past 3 months or trigger point injection within the past 6 weeks.
The study team makes the final eligibility decision.
Where it's taking place
- St Louis, Missouri, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include St Louis, Missouri, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.