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New treatment option for Addiction Nicotine
Official title The CONQUER Trial - Cessation Of Nicotine, QUitting With E-cigarette Reduction
ClinicalTrials.gov ID: NCT07322432
What this study is testing
- What it's testing
- This clinical trial evaluates the VapeAway system, a novel, multi-modal intervention designed to address the multifaceted nature of vaping addiction. VapeAway combines progressive nicotine tapering via proprietary filters, behavioral substitution with a sensory device (Fix Bar), and structured digital support.
- Phase 2: a mid-size study of how well it works
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 21 and older
You may be able to join if
- Age: Adults aged 21 years and older
- Current Vaping Behavior: Daily or near-daily use (≥5 days/week or at least 20 days per month) of nicotine-containing e-cigarettes for at least the...
- Motivation and desire to quit as determined by all of the following three assessment tools:
- Score of 4 or 5 on all 5-point Likert-type scale questions (see appendix)
- Score of 6 or 7 on Motivation To Stop Scale (MTSS) (see appendix)
You likely can't join if
- Mental Health Concerns with a score above the following thresholds:
- PHQ-2 score ≥ 2 (see appendix)
- GAD-2 score ≥ 2 (see appendix)
- Use of Other Tobacco or Nicotine Products:
- Use of any nicotine products except for vaping, including combustible tobacco (e.g., cigarettes) or other non-e-cigarette nicotine delivery systems...
- Current Substance or alcohol Use Disorder:
See the full eligibility criteria
- Age: Adults aged 21 years and older
- Current Vaping Behavior: Daily or near-daily use (≥5 days/week or at least 20 days per month) of nicotine-containing e-cigarettes for at least the past 3 months.
- Motivation and desire to quit as determined by all of the following three assessment tools:
- Score of 4 or 5 on all 5-point Likert-type scale questions (see appendix)
- Score of 6 or 7 on Motivation To Stop Scale (MTSS) (see appendix)
- Participants must be classified in the Preparation stage of the Transtheoretical Model of behavior change (see appendix)
- Saliva Cotinine level ≥ 10 ng/ml
- Penn State Electronic Cigarette Dependence Index (PSECDI) of at least 4 and above
- Willingness to participate in the study and all study requirements
- Willingness to not use any other nicotine-containing products for the duration of the study
- Ability to attend visits and provide informed consent
- Mental Health Concerns with a score above the following thresholds:
- PHQ-2 score ≥ 2 (see appendix)
- GAD-2 score ≥ 2 (see appendix)
- Use of Other Tobacco or Nicotine Products:
- Use of any nicotine products except for vaping, including combustible tobacco (e.g., cigarettes) or other non-e-cigarette nicotine delivery systems within the past 30-days
- Current Substance or alcohol Use Disorder:
- Self-reported or medically diagnosed substance use disorder (excluding nicotine), unless in sustained remission (\>12 months).
- Illicit drug use in the past 60 days
- Screening positive for alcohol use disorder in past year
- Medical Contraindications:
- Any serious medical condition or medication that would contraindicate participation in a behavioral cessation trial (to be defined and assessed by study physician or PI).
- Pregnant or breastfeeding
- Symptomatic cardiovascular disease
- Participation in another smoking/vaping cessation trial
The study team makes the final eligibility decision.
Where it's taking place
- New York, New York, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 21 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include New York, New York, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.