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New treatment option for Advanced Breast Cancer
Official title A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors
ClinicalTrials.gov ID: NCT07318805
What this study is testing
What is PF-08032562?
PF-08032562 is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for advanced breast cancer.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The purpose of this study is to learn about the safety and effects of the study medicine when given alone or together with other anti-cancer therapies. Anti-cancer therapy is a type of treatment to stop the growth of cancer.
- Phase 1: an early, usually small safety study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- 18 years of age or older
- Advanced or metastatic cancer of the breast or colon Part 1A: metastatic or advanced breast cancer or colorectal cancer for which no standard therapy...
- Measurable disease
- ECOG performance status 0 or 1
You likely can't join if
- Active malignancy within 3 years prior to enrollment
- Known symptomatic brain metastases requiring steroids
- Advanced/metastatic, symptomatic, visceral spread, that are at risk of life-threatening complications in the short term
- Prior irradiation to \>25% of the bone marrow
- Hypertension that cannot be controlled by optimal medical therapy
- Renal impairment
See the full eligibility criteria
- 18 years of age or older
- Advanced or metastatic cancer of the breast or colon Part 1A: metastatic or advanced breast cancer or colorectal cancer for which no standard therapy is available Part 1B: metastatic or advanced breast cancer with...
- Measurable disease
- ECOG performance status 0 or 1
- Active malignancy within 3 years prior to enrollment
- Known symptomatic brain metastases requiring steroids
- Advanced/metastatic, symptomatic, visceral spread, that are at risk of life-threatening complications in the short term
- Prior irradiation to \>25% of the bone marrow
- Hypertension that cannot be controlled by optimal medical therapy
- Renal impairment
- Hepatic dysfunction
- Cardiac abnormalities
- Active bleeding disorder
- Active or history of clinically significant GI disease
- Other unacceptable abnormalities as defined by protocol
The study team makes the final eligibility decision.
Where it's taking place
- Duarte, California, United States
- Grand Rapids, Michigan, United States
- Conroe, Texas, United States
- Houston, Texas, United States
- League City, Texas, United States
- San Antonio, Texas, United States
- Sugar Land, Texas, United States
- West Valley City, Utah, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Duarte, California, United States; Grand Rapids, Michigan, United States; Conroe, Texas, United States; Houston, Texas, United States; League City, Texas, United States; San Antonio, Texas, United States and 2 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.