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New treatment option for Endometrial Cancer
Official title A Study of Multiparametric Ultrasound Imaging (mpUS) for People With Endometrial Cancer
ClinicalTrials.gov ID: NCT07318415
What this study is testing
- What it's testing
- The researchers are doing this study to see how well multiparametric ultrasound (mpUS) imaging can evaluate vaginal tissue before and after IVRT. IVRT is routinely used to treat endometrial cancer but can cause damage to the vaginal tissue (vaginal toxicity).
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older, women only
You may be able to join if
- Patients must be diagnosed with a primary endometrial carcinoma. The following histologic subtypes are eligible for inclusion: endometrioid, serious...
- Initial surgical treatment must have included hysterectomy, bilateral salpingo-oophorectomy, and pelvic lymph node assessment with either sentinel...
- Patients must have had a complete surgical resection with negative margins and no residual gross disease after surgery
- Patients must have FIGO (2009) stage I-II disease (per surgical staging)
- Age ≥ 18 years
You likely can't join if
- Patients receiving chemotherapy or hormonal therapy
- A prior or concurrent malignancy whose natural history or treatment would interfere with the toxicity or how well it works assessment of IVRT
- Prior pelvic radiotherapy
- Active genitourinary infection requiring antibiotics, except for uncomplicated urinary tract infection
- History of active inflammatory bowel disease requiring treatment, including Crohn's disease and ulcerative colitis
- Concurrent psychiatric or medical condition or disease which, per investigator judgement, would make them unsuitable candidates for study enrollment
See the full eligibility criteria
- Patients must be diagnosed with a primary endometrial carcinoma. The following histologic subtypes are eligible for inclusion: endometrioid, serious, clear cell, dedifferentiated/undifferentiated, mixed epithelial...
- Initial surgical treatment must have included hysterectomy, bilateral salpingo-oophorectomy, and pelvic lymph node assessment with either sentinel lymph node mapping/sampling or pelvic lymph node dissection. Surgical...
- Patients must have had a complete surgical resection with negative margins and no residual gross disease after surgery
- Patients must have FIGO (2009) stage I-II disease (per surgical staging)
- Age ≥ 18 years
- Patients must be able to start radiotherapy within 12 weeks from date of surgery
- Patients receiving chemotherapy or hormonal therapy
- A prior or concurrent malignancy whose natural history or treatment would interfere with the toxicity or how well it works assessment of IVRT
- Prior pelvic radiotherapy
- Active genitourinary infection requiring antibiotics, except for uncomplicated urinary tract infection
- History of active inflammatory bowel disease requiring treatment, including Crohn's disease and ulcerative colitis
- Concurrent psychiatric or medical condition or disease which, per investigator judgement, would make them unsuitable candidates for study enrollment
The study team makes the final eligibility decision.
Where it's taking place
- Basking Ridge, New Jersey, United States
- Middletown, New Jersey, United States
- Montvale, New Jersey, United States
- Commack, New York, United States
- Harrison, New York, United States
- New York, New York, United States
- Uniondale, New York, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Basking Ridge, New Jersey, United States; Middletown, New Jersey, United States; Montvale, New Jersey, United States; Commack, New York, United States; Harrison, New York, United States; New York, New York, United States and 1 more location(s). Enter your location above to see the nearest site and check your eligibility.
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BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.