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New treatment option for The Application of Hyaluronic Acid on Teeth Bone Healing. Hyaluronic...
Official title Effect of Injectable Hyaluronic Acid (HYADENT BG (HA)) on Bone Healing in Extraction Sockets
ClinicalTrials.gov ID: NCT07318298
What this study is testing
- What it's testing
- Complications such as postoperative pain and delayed socket healing are relatively common following surgical extraction of mandibular third molars. Various biomaterials have been investigated to enhance wound healing and reduce postoperative morbidity.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 35. Healthy volunteers may be eligible.
You may be able to join if
- Male and female participants aged 18 to 35 years
- Presence of bilateral impacted mandibular third molars classified as Pell and Gregory Class II, Position B
- Classified as American Society of Anesthesiologists (ASA) Physical Status I
- Absence of active local infection at the surgical site (e.g., no swelling, trismus, hyperthermia)
- Ability to maintain adequate oral hygiene
You likely can't join if
- History of systemic diseases such as diabetes mellitus, hypertension, gastric ulcer, or other significant medical conditions
- Presence of severe or chronic illness requiring frequent hospitalization
- Pregnant or breastfeeding individuals
- History of cognitive or motor impairment that may interfere with study participation
- Use of anti-inflammatory or analgesic medications within two weeks before surgery
- Known allergy or hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs)
See the full eligibility criteria
- Male and female participants aged 18 to 35 years
- Presence of bilateral impacted mandibular third molars classified as Pell and Gregory Class II, Position B
- Classified as American Society of Anesthesiologists (ASA) Physical Status I
- Absence of active local infection at the surgical site (e.g., no swelling, trismus, hyperthermia)
- Ability to maintain adequate oral hygiene
- Ability to understand and provide written informed consent
- Ability to read and understand Arabic or English
- Willingness to comply with study procedures and follow-up visits
- History of systemic diseases such as diabetes mellitus, hypertension, gastric ulcer, or other significant medical conditions
- Presence of severe or chronic illness requiring frequent hospitalization
- Pregnant or breastfeeding individuals
- History of cognitive or motor impairment that may interfere with study participation
- Use of anti-inflammatory or analgesic medications within two weeks before surgery
- Known allergy or hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs)
- Current smoker
- Use of anticoagulant therapy
- Any condition that, in the investigator's judgment, may interfere with healing or study outcomes
The study team makes the final eligibility decision.
Where it's taking place
- Irbid, Jordan
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 35 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Irbid, Jordan. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.