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New treatment option for Type A Aortic Dissection With Residual Type B Dissection
Official title Creation of a Digital Twin for Predicting the Progression of Patients With Chronic Thoracic Aortic Dissection
ClinicalTrials.gov ID: NCT07315178
What this study is testing
What is blood sampling?
blood sampling is an investigational medicine, being studied as a potential treatment for type a aortic dissection with residual type b dissection.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Aortic dissection causes a tear in the inner layers of the aorta, leading to the formation of a true and false lumen. There are two types of dissection: type A, which affects the ascending aorta, and type B, which affects the descending aorta.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Person who has given written consent
- Age \> 18 years
- Patient with type A aortic dissection with surgical indication for replacement
- Patient with chronic type B aortic dissection, monitored and managed medically, not operated on
You likely can't join if
- Persons not affiliated with or not covered by a social security scheme
- Persons subject to legal protection measures (guardianship)
- Persons subject to judicial protection measures
- Pregnant women, women in labour or breastfeeding
- Adults who are incapacitated or unable to give their consent
- Contraindications to MRI: claustrophobia, non-MRI-compatible metal implants, suspected metal foreign body
See the full eligibility criteria
- Person who has given written consent
- Age \> 18 years
- Patient with type A aortic dissection with surgical indication for replacement
- Patient with chronic type B aortic dissection, monitored and managed medically, not operated on
- Persons not affiliated with or not covered by a social security scheme
- Persons subject to legal protection measures (guardianship)
- Persons subject to judicial protection measures
- Pregnant women, women in labour or breastfeeding
- Adults who are incapacitated or unable to give their consent
- Contraindications to MRI: claustrophobia, non-MRI-compatible metal implants, suspected metal foreign body
- Severe renal failure (clearance \<30ml/min according to Cockroft due to gadolinium injection)
- Uncontrolled asthma
- Patients with acute type A aortic dissection who died during or in the post-operative period following surgery to repair the dissection
- Patients with a known allergy to gadolinium-based contrast agents
- Patients treated for type B aortic dissection who underwent surgery
The study team makes the final eligibility decision.
Where it's taking place
- Dijon, France
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Dijon, France. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.