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New treatment option for Healthy Volunteer Study
Official title Drug-drug Interaction Study of Bemnifosbuvir/Ruzasvir (BEM/RZR) and Buprenorphine/Naloxone or Methadone
ClinicalTrials.gov ID: NCT07314346
What this study is testing
What is Buprenorphine/Naloxone + BEM/RZR?
Buprenorphine/Naloxone + BEM/RZR is an investigational medicine, being studied as a potential treatment for healthy volunteer study.
Also referred to as BEM (AT-527)/RZR (AT-038).
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Drug-drug interaction study between Bemnifosbuvir/Ruzasvir (BEM/RZR) and Buprenorphine/Naloxone or Methadone
- Phase 1: an early, usually small safety study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65. Healthy volunteers may be eligible.
You may be able to join if
- Must agree to use acceptable contraceptive methods through at least 90 days after the last dose of study drug.
- Minimum body weight of 50 kg and body mass index (BMI) of 18-32 kg/ m2.
- Willing to comply with the study requirements and to provide written informed consent.
You likely can't join if
- Infected with hepatitis B virus, hepatitis C virus, HIV.
- Abuse of alcohol or drugs.
- Use of other investigational drugs within 28 days prior to Day -5.
- Concomitant use of prescription medications, or systemic over-the-counter medications (apart from methadone or buprenorphine/naloxone as assigned...
- Other clinically significant medical conditions or laboratory abnormalities.
The study team makes the final eligibility decision.
Where it's taking place
- Hollywood, Florida, United States
- Overland Park, Kansas, United States
- Marlton, New Jersey, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Hollywood, Florida, United States; Overland Park, Kansas, United States; Marlton, New Jersey, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.