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New treatment option for Acute Respiratory Syndrome Distress
Official title EIT-Guided PEEP Optimization in Trauma and Postoperative ARDS
ClinicalTrials.gov ID: NCT07313644
What this study is testing
- What it's testing
- Acute respiratory distress syndrome (ARDS) remains a serious and often fatal complication in patients following severe trauma or major surgery. Mechanical ventilation is essential for supportive care in this population, but may aggravate lung injury when suboptimal ventilatory settings are applied.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 90
You may be able to join if
- Mechanically ventilated surgical intensive care patients with trauma- or postoperative-associated moderate to severe ARDS, as defined by the 2023...
You likely can't join if
- Age \ 90 years.
- Severe acute brain injury or acute stroke with Glasgow Coma Scale \<8.
- Thoracic trauma with pneumothorax or pneumomediastinum.
- End-stage diseases under palliative care (e.g., metastatic cancer, cirrhosis, end-stage renal disease).
- Severe multiorgan failure with expected survival \<7 days.
- Conditions requiring prolonged mechanical ventilation (e.g., Guillain-Barré syndrome, cervical spinal cord injury).
See the full eligibility criteria
- Mechanically ventilated surgical intensive care patients with trauma- or postoperative-associated moderate to severe ARDS, as defined by the 2023 Global Definition of ARDS.
- Age \ 90 years.
- Severe acute brain injury or acute stroke with Glasgow Coma Scale \<8.
- Thoracic trauma with pneumothorax or pneumomediastinum.
- End-stage diseases under palliative care (e.g., metastatic cancer, cirrhosis, end-stage renal disease).
- Severe multiorgan failure with expected survival \<7 days.
- Conditions requiring prolonged mechanical ventilation (e.g., Guillain-Barré syndrome, cervical spinal cord injury).
- Contraindications to hypercapnia (e.g., elevated intracranial pressure, acute coronary syndrome).
- Prior use of advanced respiratory therapies (e.g., ECMO, inhaled nitric oxide, prone positioning, high-frequency ventilation).
- Pregnancy, breastfeeding, or skin lesions at electrode placement sites.
- Implanted electrical devices interfering with EIT (e.g., pacemaker, ICD).
- Known allergy to electrode materials.
- Refusal to participate or concurrent enrollment in another study
The study team makes the final eligibility decision.
Where it's taking place
- Hanoi, Vietnam
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 90 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Hanoi, Vietnam. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.