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New treatment option for Sleep
Official title Sleep and Morning Wellbeing Study
ClinicalTrials.gov ID: NCT07311434
What this study is testing
- What it's testing
- The study will be a prospective randomized, controlled clinical study. There will be interventional treatment for a total of 30 days.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 22 to 59. Healthy volunteers may be eligible.
You may be able to join if
- Male or female.
- Age 25-59 years.
- BMI ≥18.5 and ≤29.9 kg/m².
- Currently experiencing issues with sleep quality, falling asleep, staying asleep, or waking during the night.
- RU-SATED score ≤17.
You likely can't join if
- Diagnosed chronic sleep conditions (e.g., insomnia, narcolepsy, REM Behavior Disorder, moderate to severe restless leg syndrome, sleep apnea).
- Current use of sleep-tracking technology (e.g., wrist-worn trackers, rings, smartphone apps) that could influence sleep behavior or perception. Women...
- Use of hormone therapy (estrogen, progesterone, phytoestrogens) within the last 3 months.
- Diagnosed psychiatric disorders including major depressive disorder with acute symptoms, bipolar disorder, generalized anxiety disorder with active...
- Diagnosed neurodegenerative or chronic pain disorders, including Parkinson's disease, Alzheimer's disease, or uncontrolled fibromyalgia.
- Regular prescribed stimulant use (e.g., amphetamines such as Adderall/Vyvanse; methylphenidate such as Ritalin/Concerta; modafinil/armodafinil).
See the full eligibility criteria
- Male or female.
- Age 25-59 years.
- BMI ≥18.5 and ≤29.9 kg/m².
- Currently experiencing issues with sleep quality, falling asleep, staying asleep, or waking during the night.
- RU-SATED score ≤17.
- Willing and able to follow the study protocol.
- Willing to discontinue any other supplements (including nootropics, adaptogens, calming herbs), medications, herbal remedies, or over-the-counter sleep medications (e.g., zolpidem, diphenhydramine, Benadryl, ZzzQuil...
- Agree to limit alcohol intake within approximately 4 hours of bedtime throughout participation.
- Agree to limit caffeine intake to ≤400 mg/day (about 3-4 cups of coffee) and avoid ingestion of caffeine-containing products after 2:00 PM during the study period.
- Generally healthy and not living with any uncontrolled chronic disease.
- Resides in the United States.
- Willing to discontinue any restricted products and adhere to all required study assessments.
- Diagnosed chronic sleep conditions (e.g., insomnia, narcolepsy, REM Behavior Disorder, moderate to severe restless leg syndrome, sleep apnea).
- Current use of sleep-tracking technology (e.g., wrist-worn trackers, rings, smartphone apps) that could influence sleep behavior or perception. Women currently undergoing perimenopause or experiencing vasomotor symptoms...
- Use of hormone therapy (estrogen, progesterone, phytoestrogens) within the last 3 months.
- Diagnosed psychiatric disorders including major depressive disorder with acute symptoms, bipolar disorder, generalized anxiety disorder with active symptoms, and PTSD with frequent nightmares.
- Diagnosed neurodegenerative or chronic pain disorders, including Parkinson's disease, Alzheimer's disease, or uncontrolled fibromyalgia.
- Regular prescribed stimulant use (e.g., amphetamines such as Adderall/Vyvanse; methylphenidate such as Ritalin/Concerta; modafinil/armodafinil).
- Current use of CNS-activating antidepressants (bupropion, fluoxetine, venlafaxine, sertraline).
- Current or recent use of cannabis or THC-containing products (recreational or medicinal marijuana, CBD with measurable THC, synthetic cannabinoids) within the past 30 days.
- Employment in jobs disrupting nighttime sleep (e.g., night shift, rotating shift, excessive travel).
- Current use of prescription sleep aids.
- Introduction of any new sleep-related supplements, medications, herbal remedies, or melatonin products during the study.
- Use of any prescription or OTC products with sedative properties (e.g., melatonin, diphenhydramine, doxylamine, valerian, ZzzQuil, Advil PM) within 4 weeks prior to enrollment or habitual use ≥3 times per week prior to...
- Allergy or sensitivity to any study product ingredients.
- Pregnant, breastfeeding, or trying to conceive during the study period.
- History of substance abuse.
- Heavy alcohol use (≥8 drinks/week for women or ≥15 drinks/week for men).
- Participation in another research study now or within the next 7 weeks.
- Any condition or behavior that, in the investigator's judgment, may interfere with study participation or data integrity.
The study team makes the final eligibility decision.
Where it's taking place
- San Francisco, California, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 22 years to 59 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include San Francisco, California, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.