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Compares treatment options for Coronary Artery Bypass Graft (CABG)
Official title Aortic No-Touch vs Partial Aortic Clamping in Off-Pump CABG
ClinicalTrials.gov ID: NCT07302659
What this study is testing
- What it's testing
- To explore surgical strategies that reduce perioperative neurologic complications in cardiovascular surgery, with the aim of improving perioperative outcomes and quality of life while reducing the socioeconomic burden. Specifically: This multicenter, randomized controlled clinical trial will evaluate the benefits of a novel aortic no-touch technique in reducing perioperative silent brain infarction(SBI) among patients undergoing surgical treatment for coronary artery disease.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Adult patients (\>18 years old) with multivessel coronary artery disease who are scheduled to undergo isolated off-pump coronary artery bypass...
You likely can't join if
- Indications for cardiopulmonary bypass surgery (or no contraindications to on-pump surgery);
- Great saphenous vein is unsuitable for use as a graft conduit;
- Subclavian artery stenosis or occlusion, or any contraindication to the use of the internal mammary artery as a graft conduit;
- History of previous cardiac surgery;
- Emergency surgery;
- Inability to apply an aortic clamp due to severe ascending aortic calcification;
See the full eligibility criteria
- Adult patients (\>18 years old) with multivessel coronary artery disease who are scheduled to undergo isolated off-pump coronary artery bypass grafting and who provide informed consent to participate in this study.
- Indications for cardiopulmonary bypass surgery (or no contraindications to on-pump surgery);
- Great saphenous vein is unsuitable for use as a graft conduit;
- Subclavian artery stenosis or occlusion, or any contraindication to the use of the internal mammary artery as a graft conduit;
- History of previous cardiac surgery;
- Emergency surgery;
- Inability to apply an aortic clamp due to severe ascending aortic calcification;
- Expected inability to tolerate MRI or contraindications to MRI (e.g., known intolerance to MRI, an implanted permanent pacemaker, or an anticipated need for permanent pacemaker implantation);
- Inability to complete neurocognitive assessment due to language barriers or visual/hearing impairment.
The study team makes the final eligibility decision.
Where it's taking place
- Beijing, China
- Qingdao, China
- Shenzhen, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Beijing, China; Qingdao, China; Shenzhen, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.