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Compares treatment options for Decompensated Cirrhosis Ethanol Related
Official title Effect of Whey Protein Versus Egg Albumen Protein Challenge on Blood Ammonia Level in Patients of Decompensated Ethanol Related Cirrhosis.
ClinicalTrials.gov ID: NCT07299110
What this study is testing
- What it's testing
- In cirrhosis, altered nitrogen metabolism and reduced hepatic clearance of ammonia contribute to the development of Minimal Hepatic Encephalopathy (MHE)-a subclinical but functionally debilitating condition. While adequate protein intake is essential to prevent sarcopenia in cirrhotic patients, the type of protein consumed can significantly influence postprandial ammonia generation, thereby affecting neurocognitive status.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 70
You may be able to join if
- Known or newly diagnosed (clinical, imaging) case of decompensated ethanol related cirrhosis patients.
- Age (18-70 years).
- Informed consent to participate in the study.
You likely can't join if
- History of overt HE (West Haven grade II or more).
- Last Intake \<1.5 months.
- CKD (creatinine \>1.5 mg/dL), active infection, GI bleeding in past 2 weeks.
- Severe anaemia (Hb \<7 g/dL) or hypoalbuminemia (\<2.0 g/dL).
- Known egg or dairy allergy.
- Those on sedatives, antidepressant or anti-psychiatric medication.
See the full eligibility criteria
- Known or newly diagnosed (clinical, imaging) case of decompensated ethanol related cirrhosis patients.
- Age (18-70 years).
- Informed consent to participate in the study.
- History of overt HE (West Haven grade II or more).
- Last Intake \<1.5 months.
- CKD (creatinine \>1.5 mg/dL), active infection, GI bleeding in past 2 weeks.
- Severe anaemia (Hb \<7 g/dL) or hypoalbuminemia (\<2.0 g/dL).
- Known egg or dairy allergy.
- Those on sedatives, antidepressant or anti-psychiatric medication.
- Unable to understand the language or instructions.
- Hepatocellular Carcinoma.
- TIPS.
- Receiving rifaximin or lactulose.
- Diarrhea, SIBO or malabsorptive syndrome.
The study team makes the final eligibility decision.
Where it's taking place
- New Delhi, India
Compensation & support
A stipend or compensation may be offered.
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 70 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include New Delhi, India. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.