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New treatment option for Nicotine Addiction
Official title Non-Invasive Deep Brain Neuromodulation for Smoking Cessation
ClinicalTrials.gov ID: NCT07298902
What this study is testing
- What it's testing
- This study will develop novel low intensity focused ultrasound (LIFU) therapy to help people to quit cigarette smoking. Smoking is associated with cancers of the lung.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 20 to 60. Healthy volunteers may be eligible.
You may be able to join if
- Must be a smoker for 5 or more years and within 20 to 60 years of age
- Must not meet
You likely can't join if
- for MRI scanning (e.g., non-fixed magnetizable objects)
- Must not have ongoing unstable medical, neurological or psychiatric illness as determined by a combination of history, medical record, and/or...
- Must be a current smoker with average of 5 cigarettes or more a day for the last month or longer.
- Report 3 or more trials of smoking cessation attempts using nicotine replacement, e-cig, TMS, varenicline or other smoking cessation drugs...
- Failed TMS screening questionnaire.
- Significant alcohol or other drug use (substance dependence within the recent months) or positive urine toxicology screen for substance not...
See the full eligibility criteria
- Must be a smoker for 5 or more years and within 20 to 60 years of age
- Must not meet
- for MRI scanning (e.g., non-fixed magnetizable objects)
- Must not have ongoing unstable medical, neurological or psychiatric illness as determined by a combination of history, medical record, and/or examination.
- Must be a current smoker with average of 5 cigarettes or more a day for the last month or longer.
- Report 3 or more trials of smoking cessation attempts using nicotine replacement, e-cig, TMS, varenicline or other smoking cessation drugs, psychotherapy or other means. Exclusion Criteria:
- Failed TMS screening questionnaire.
- Significant alcohol or other drug use (substance dependence within the recent months) or positive urine toxicology screen for substance not prescribed other than nicotine or marijuana dependence.
- Cannot refrain from using alcohol and/or marijuana 24 hours or more prior to experiments.
- Taking \> 400 mg clozapine/day and not on anti-seizure medication(s) with sufficient dose.
- Woman who is pregnant (child-bearing potential but not on contraceptive and missing menstrual period; or by self-report; or by positive pregnancy test) or has had unprotected sexual intercourse without birth control in...
- In ongoing smoking cessation treatment, clinical trial, or nicotine replacements (except for the current study)
The study team makes the final eligibility decision.
Where it's taking place
- Houston, Texas, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 20 years to 60 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Houston, Texas, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.