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Compares treatment options for Perioperative Respiratory Mechanics
Official title Effect of Sevoflurane vs Desflurane on Mechanical Power in Laparoscopic Cholecystectomy
ClinicalTrials.gov ID: NCT07295158
What this study is testing
What is Sevoflurane?
Sevoflurane is an investigational medicine, given as an inhaled treatment, being studied as a potential treatment for perioperative respiratory mechanics.
Also referred to as Group S.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This single-center, prospective, randomized, assessor-blinded clinical trial aims to compare the effects of sevoflurane and desflurane anesthesia on intraoperative mechanical power in adult patients undergoing elective laparoscopic cholecystectomy. Mechanical power will be measured at three standardized time points using a validated formula, and secondary outcomes include driving pressure values and early postoperative respiratory complications (desaturation, laryngospasm, bronchospasm, cough).
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- Adults aged 18-65 years
- ASA Physical Status I-II
- Scheduled for elective laparoscopic cholecystectomy
- Able to provide written informed consent
You likely can't join if
- Known hypersensitivity or contraindication to study medications (sevoflurane or desflurane)
- Severe chronic obstructive pulmonary disease (COPD)
- Uncontrolled bronchial asthma
- Decompensated heart failure (NYHA Class III-IV)
- History of prior lung surgery
- Morbid obesity (BMI \> 35 kg/m²)
See the full eligibility criteria
- Adults aged 18-65 years
- ASA Physical Status I-II
- Scheduled for elective laparoscopic cholecystectomy
- Able to provide written informed consent
- Known hypersensitivity or contraindication to study medications (sevoflurane or desflurane)
- Severe chronic obstructive pulmonary disease (COPD)
- Uncontrolled bronchial asthma
- Decompensated heart failure (NYHA Class III-IV)
- History of prior lung surgery
- Morbid obesity (BMI \> 35 kg/m²)
- Pregnancy
- Refusal to participate or inability to provide informed consent
The study team makes the final eligibility decision.
Where it's taking place
- Konya, Konya, Turkey (Türkiye)
Compensation & support
A stipend or compensation may be offered.
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Konya, Konya, Turkey (Türkiye). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.