BridgeMD
New treatment option for Kidney Transplantation, Cytomegalovirus Infections
Official title Is Valacyclovir Non-inferior to Valganciclovir as CMV and EBV Prophylaxis in Kidney Transplant Recipients? A Single-Center Prospective Randomized Pilot Study
ClinicalTrials.gov ID: NCT07294547
What this study is testing
What is Valacyclovir (Valtrex)?
Valacyclovir (Valtrex) is an investigational medicine, given as an once-daily pill taken by mouth, being studied as a potential treatment for kidney transplantation, cytomegalovirus infections.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Opportunistic CMV viremia (primary infection or reactivation) is usually managed by taking prophylactic medication for both adult and pediatric kidney transplant patients. Most hospitals prescribe valganciclovir for this purpose but valacyclovir has also been used.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 3 and older
You may be able to join if
- Age at least 3 years of age
- Patients who are about to receive or just received kidney transplantation within the past 2 weeks before the date of screening.
- Will be receiving prophylactic antiviral therapy against CMV and/or EBV per discretion of transplant surgeon
- No active CMV or EBV viremia (as defined by detectable viral load PCR) at the time of screening.
- Ability and willingness of the patient (or parent/legal guardian for minors) to provide informed consent and comply with study procedures.
You likely can't join if
- Severe co-morbidities that would preclude safe participation as judged by the transplant surgeon
- Pregnancy (valganciclovir is likely teratogenic)
- Known allergy to both valacyclovir and valganciclovir
The study team makes the final eligibility decision.
Where it's taking place
- Taipei, Taiwan
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 3 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Taipei, Taiwan. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.