Recruiting PHASE2, PHASE3 Post Operative Analgesia

New treatment option for Post Operative Analgesia

Official title Comparative Analysis Of Dexmedetomidine And Dexamethasone As An Adjuvant To 0.5%Ropivacaine On Onset Of Ultrasound Guided Supraclavicular Brachial Plexus Block In Patients Undergoing Upper Limb Surgeries

ClinicalTrials.gov ID: NCT07290595

What this study is testing

What is Ropivacaine + Dexmedetomidine?

Ropivacaine + Dexmedetomidine is an investigational medicine, being studied as a potential treatment for post operative analgesia.

Also referred to as Supravlavicular Brachial Plexus Block with Ropivacaine and Dexmedetomidine.

Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.

What it's testing
To compare the efficacy of dexmedetomidine and dexamethasone as an adjuvant to 0.5%ropivacaine on onset of ultrasound guided supraclavicular brachial plexus block in patients undergoing upper limb surgeries. Ropivacaine hydrochloride, a long acting local anesthetic, is commonly used for supraclavicular block owing to its favorable safety profile especially in terms of minimal cardiotoxicity and less motor block.
  • Phase 3: a large, late-stage study
  • Which group you join is decided by chance.

A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.

Who can take part

Ages 18 to 70. Healthy volunteers may be eligible.

You may be able to join if

  • Patients scheduled for upper limb surgery below mid-humerus level
  • Patients aged 18 to 70 years
  • Patients with ASA class I, II and III
  • Male and non-pregnant females

You likely can't join if

  • Patients refusal
  • Patients with pre-existing peripheral neuropathy of the upper limb
  • Patients with the Infection at block site
  • Patients with history of ischemic heart disease
  • Patients with bleeding disorder or deranged coagulation profile
  • Patients with known history of allergy to local anaesthetic or any other drugs used

The study team makes the final eligibility decision.

Where it's taking place

  • Sāhīwāl, Punjab Province, Pakistan

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 18 years to 70 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.

Where is this trial taking place?

Study sites include Sāhīwāl, Punjab Province, Pakistan. Enter your location above to see the nearest site and check your eligibility.

Explore other conditions

BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.