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New treatment option for Clostridioides Difficile Associated Disease
Official title A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older
ClinicalTrials.gov ID: NCT07282665
What this study is testing
What is C.difficile vaccine?
C.difficile vaccine is an investigational medicine, given as an injection into a muscle, being studied as a potential treatment for clostridioides difficile associated disease.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The purpose of the study is to learn about how effective, safe, and tolerable the Clostridioides difficile (C. difficile) vaccine is in decreasing the number of C.
- Phase 3: a large, late-stage study
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 65 and older. Healthy volunteers may be eligible.
You may be able to join if
- Who Can Join the Study ():
- People with recent or future planned contact with healthcare systems or who have recently received antibiotics. Who Cannot Join the Study (
You likely can't join if
- Anyone who has had CDI before.
- Anyone who has had surgery to remove part of their small or large intestine.
- Anyone who often has diarrhea (meaning three or more loose stools in a day, more than once a month).
- Anyone who has already received a vaccine or special antibody treatment for C. difficile.
- Anyone who has had a serious allergic reaction to a vaccine or to any part of the study vaccines.
- Anyone who might not respond well to the vaccine because their immune system is weak (either from a disease or from treatment).
See the full eligibility criteria
- Who Can Join the Study ():
- People with recent or future planned contact with healthcare systems or who have recently received antibiotics. Who Cannot Join the Study (
- Anyone who has had CDI before.
- Anyone who has had surgery to remove part of their small or large intestine.
- Anyone who often has diarrhea (meaning three or more loose stools in a day, more than once a month).
- Anyone who has already received a vaccine or special antibody treatment for C. difficile.
- Anyone who has had a serious allergic reaction to a vaccine or to any part of the study vaccines.
- Anyone who might not respond well to the vaccine because their immune system is weak (either from a disease or from treatment).
- Anyone with cancer that has spread, kidney failure, or another serious health problem.
The study team makes the final eligibility decision.
Where it's taking place
- Athens, Alabama, United States
- Guntersville, Alabama, United States
- Huntsville, Alabama, United States
- Sun City, Arizona, United States
- Little Rock, Arkansas, United States
- Daly City, California, United States
- Los Angeles, California, United States
- Mather, California, United States
- Oakland, California, United States
- Ontario, California, United States
- Pasadena, California, United States
- Roseville, California, United States
- Sacramento, California, United States
- San Bernardino, California, United States
- San Diego, California, United States
- San Jose, California, United States
- San Mateo, California, United States
- Santa Clara, California, United States
- Toluca Lake, California, United States
- Walnut Creek, California, United States
+ 107 more site(s).
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 65 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Athens, Alabama, United States; Guntersville, Alabama, United States; Huntsville, Alabama, United States; Sun City, Arizona, United States; Little Rock, Arkansas, United States; Daly City, California, United States and 121 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.