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New treatment option for Atrioventricular Block
Official title Central Haemodynamics and Pacing for AV Block
ClinicalTrials.gov ID: NCT07276490
What this study is testing
- What it's testing
- A randomized, single-blind study comparing two pacing strategies in patients with atrioventricular block requiring permanent pacemaker implantation. This trial evaluates the impact of conduction system pacing (left bundle branch area pacing) versus standard right ventricular pacing on central hemodynamics, cardiac function, and patient quality of life over 12 months.
- Time commitment: about 12 months
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- Age 18-80 years
- Diagnosis of atrioventricular block
- Expected survival \>1 year
You likely can't join if
- Reduced left ventricular ejection fraction (EF \<45%)
- Expected ventricular pacing burden \<20%
- Inter-arm systolic blood pressure difference \>15 mmHg
- Percutaneous coronary intervention or coronary artery bypass surgery within the last 30 days
- Secondary hypertension
- Orthostatic hypotension
See the full eligibility criteria
- Age 18-80 years
- Diagnosis of atrioventricular block
- Expected survival \>1 year
- Reduced left ventricular ejection fraction (EF \<45%)
- Expected ventricular pacing burden \<20%
- Inter-arm systolic blood pressure difference \>15 mmHg
- Percutaneous coronary intervention or coronary artery bypass surgery within the last 30 days
- Secondary hypertension
- Orthostatic hypotension
- Clinically significant valvular heart disease
- Congenital heart disease
- Pulse wave analysis or pulse wave velocity measurement cannot be reliably performed
- Pregnancy or breastfeeding
- Withdrawal of consent by the subject
- Loss of contact during the study
The study team makes the final eligibility decision.
Where it's taking place
- Tallinn, Harju, Estonia
- Tartu, Tartu, Estonia
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 12 months per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Tallinn, Harju, Estonia; Tartu, Tartu, Estonia. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.