BridgeMD
New treatment option for Periodontis
Official title Evaluation of the Association Between the Effects of Generalized Stage 3 and 4 Periodontitis on Arterial Stiffness and Cardiovascular Risk: the PAROCAR Study
ClinicalTrials.gov ID: NCT07263113
What this study is testing
- What it's testing
- Periodontal diseases are chronic inflammatory conditions affecting nearly half of the adult population and are associated with systemic inflammatory responses. Recent evidence suggests a possible link between severe periodontitis and cardiovascular diseases through shared inflammatory pathways.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 40 to 69. Healthy volunteers may be eligible.
You may be able to join if
- Age 40-69 years
- Minimum of 12 teeth (3 per quadrant)
- Written informed consent Exposed group: generalized periodontitis stage 3 or 4 (Chicago 2017 Classification) Non-exposed group: healthy periodontium
You likely can't join if
- Patients diagnosed with diabetes,
- Patients diagnosed with hypertension or with a history of severe cardiovascular disease,
- Patients diagnosed with familial hypercholesterolaemia,
- Patients with a medical history or current condition that, in the investigator's opinion, is likely to interfere with the study results,
- Patients with a BMI ≥ 30 kg/m²,
- Patients who have previously undergone periodontal treatment,
See the full eligibility criteria
- Age 40-69 years
- Minimum of 12 teeth (3 per quadrant)
- Written informed consent Exposed group: generalized periodontitis stage 3 or 4 (Chicago 2017 Classification) Non-exposed group: healthy periodontium
- Patients diagnosed with diabetes,
- Patients diagnosed with hypertension or with a history of severe cardiovascular disease,
- Patients diagnosed with familial hypercholesterolaemia,
- Patients with a medical history or current condition that, in the investigator's opinion, is likely to interfere with the study results,
- Patients with a BMI ≥ 30 kg/m²,
- Patients who have previously undergone periodontal treatment,
- Patients who consume more than 2 units of alcohol per day,
- Patients who refuse to participate in the study,
- Minors and patients under the age of 40,
- Adult patients under legal protection (guardianship, curatorship),
- Patients deprived of their liberty,
- Pregnant or breastfeeding women,
- Patients not affiliated with a health insurance scheme (AME)
- Patients already included in another treatment study
The study team makes the final eligibility decision.
Where it's taking place
- Nantes, France
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 40 years to 69 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Nantes, France. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.