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New treatment option for Periodontal Disease
Official title Salivary Mitofusin-1 Levels in Periodontitis: Associations With Disease Severity, Smoking, and Treatment Response
ClinicalTrials.gov ID: NCT07262606
What this study is testing
- What it's testing
- Periodontitis (gum inflammation) is a common disease worldwide. This study aims to investigate a novel biomarker, a protein called Mitofusin-1 (Mfn1), in saliva that may be associated with the severity of periodontitis and response to treatment.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65. Healthy volunteers may be eligible.
You may be able to join if
- Willing and able to provide written informed consent.
- Systemically healthy (no history of diabetes mellitus, immunodeficiency, malignancy, or other systemic conditions that could affect periodontal...
- Have a minimum of 20 natural teeth (excluding third molars).
- No antibiotic therapy or periodontal treatment in the last 6 months. For Healthy Control Group: No clinical attachment loss. Probing depth ≤ 3 mm. No...
You likely can't join if
- Fewer than 20 natural teeth (excluding third molars).
- Presence of any systemic disease (e.g., diabetes mellitus, immunological disorders, cancer).
- Use of antibiotics or receiving periodontal treatment in the last 6 months.
- Pregnancy or lactation.
- For non-periodontitis groups (Healthy Control): Any signs of periodontitis.
- For periodontitis groups (all): History of smoking cessation for at least 5 years (must be either a current regular smoker or a never-smoker...
The study team makes the final eligibility decision.
Where it's taking place
- Erzincan, Erzincan, Turkey (Türkiye)
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Erzincan, Erzincan, Turkey (Türkiye). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.