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Prevention study for Periodontal Disease
Official title Oral-Spray Bacillus Spore Probiotics for Periodontal Disease Prevention and Supprotive Treatment in the Elderly
ClinicalTrials.gov ID: NCT07258303
What this study is testing
What is oral-spray 0.9% NaCl physiological saline solution?
oral-spray 0.9% NaCl physiological saline solution is an investigational medicine, given as an once-daily infusion into a vein, being studied as a potential treatment for periodontal disease.
Also referred to as Registration number: VD-32723-19.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Periodontal diseases are strongly associated with dysbiosis of the oral microbiome within the biofilm. Key pathogens, including Streptococcus mutans, Aggregatibacter actinomycetemcomitans, and Porphyromonas gingivalis, contribute to caries progression and periodontal inflammation.
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 35 and older. Healthy volunteers may be eligible.
You may be able to join if
- Patients aged 35 years and older.
- Patients diagnosed with periodontal disease based on clinical examination, including gingivitis and periodontitis.
- Patients presenting with at least 10 natural teeth in the dental arch.
- Patients with stable general health status and able to comply with study procedures.
- Patients (or their legal guardians) who provide written informed consent and voluntarily agree to participate in the study.
You likely can't join if
- Patients with unstable general health, acute systemic or oral diseases, or malignant conditions that may interfere with participation.
- Patients who are currently receiving treatment for periodontal disease at specialized dental facilities.
- Patients currently using any therapeutic or adjunctive products for the management of periodontal disease.
The study team makes the final eligibility decision.
Where it's taking place
- Hanoi, Hanoi, Vietnam
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 35 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Hanoi, Hanoi, Vietnam. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.