BridgeMD
Compares treatment options for PCOS
Official title Cabergoline & Letrozole Versus Letrozole in Ovulation Induction in PCOS
ClinicalTrials.gov ID: NCT07255911
What this study is testing
What is Letrozole 0.5mg?
Letrozole 0.5mg is an investigational medicine, given as an once-daily pill taken by mouth, being studied as a potential treatment for pcos.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Does combined Cabergoline and letrozole increase ovulation rate What medical problems do participants have when taking drug Cabergoline and Letrozole ? Researchers will compare drug combination of Cabergoline and letrozole to letrozole alone to see combined cabergoline and letrozole works better as ovulation induction.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 35, women only
You may be able to join if
- PCOS patients diagnosed according to Rotterdam criteria.
- Age: 18-35 years.
- Primary or secondary subfertility.
- Selected for ovulation induction.
You likely can't join if
- Women suffered from PCOS like symptom ex. Late onset congenital adrenal hyperplasia, Cushing syndrome.
- Serum prolactin (more than 50 ng/ml) (Kyritsi et al., 2018).
- Male factor infertility.
- Women with other infertility factors (endometriosis, PID,uterine \& tubal causes of infertility).
- Uncontrolled Medical disease (DM, HTN, kidney disease, liver disease).
- History of hypersensitivity to cabergoline \& letrozole.
See the full eligibility criteria
- PCOS patients diagnosed according to Rotterdam criteria.
- Age: 18-35 years.
- Primary or secondary subfertility.
- Selected for ovulation induction.
- Women suffered from PCOS like symptom ex. Late onset congenital adrenal hyperplasia, Cushing syndrome.
- Serum prolactin (more than 50 ng/ml) (Kyritsi et al., 2018).
- Male factor infertility.
- Women with other infertility factors (endometriosis, PID,uterine \& tubal causes of infertility).
- Uncontrolled Medical disease (DM, HTN, kidney disease, liver disease).
- History of hypersensitivity to cabergoline \& letrozole.
- Thyroid dysfunction ( serum TSH ≥5mIU/L)
- BMI:\< 18.5 kg/m2 and ≥30 kg/m2.
- Patients on metformin therapy.
- Patient on antiemetic like Domperidone metoclopramide, antipsychotic drug like haloperidol and risperidone, tricyclic antidepressant like amitriptyline, clomipramine, antihypertensive like verapamil, methyldopa...
The study team makes the final eligibility decision.
Where it's taking place
- Dhaka, Shahbag, Bangladesh
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18 years to 35 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Dhaka, Shahbag, Bangladesh. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.