BridgeMD
New treatment option for Osteoporosis Postmenopausal
Official title Effect of Mechanical Loading and Bone Loss on Motor Neuron Activity-H-Reflex Relationship
ClinicalTrials.gov ID: NCT07253493
What this study is testing
- What it's testing
- Weight-bearing exercises (e.g., running, jumping, whole-body vibration) are widely practiced due to their beneficial effects on bone development and their role in the prevention and treatment of osteoporosis. However, the underlying neuroregulatory mechanisms responsible for these positive effects have not yet been fully understood.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65, women only. Healthy volunteers may be eligible.
You may be able to join if
- Being in the postmenopausal period
- For the osteoporosis group: having femoral osteoporosis (femoral neck or total femur T-score ≤ -2.5)
- For the control group: having no osteoporosis or osteopenia (femoral neck and total femur T-scores \> -1, and L1-L4 and L2-L4 T-scores \> -1)
- Being a volunteer
You likely can't join if
- Receiving osteoporosis treatment
- Having a peripheral or central nervous system disorder (e.g., stroke, polyneuropathy, radiculopathy, entrapment neuropathy, etc.)
- Having acquired or hereditary muscle diseases (myopathies)
- Having active painful lower extremity pathologies (e.g., osteoarthritis, inflammatory joint diseases, etc.)
- Having cardiac arrhythmias
- Having a history of other metabolic bone diseases
See the full eligibility criteria
- Being in the postmenopausal period
- For the osteoporosis group: having femoral osteoporosis (femoral neck or total femur T-score ≤ -2.5)
- For the control group: having no osteoporosis or osteopenia (femoral neck and total femur T-scores \> -1, and L1-L4 and L2-L4 T-scores \> -1)
- Being a volunteer
- Receiving osteoporosis treatment
- Having a peripheral or central nervous system disorder (e.g., stroke, polyneuropathy, radiculopathy, entrapment neuropathy, etc.)
- Having acquired or hereditary muscle diseases (myopathies)
- Having active painful lower extremity pathologies (e.g., osteoarthritis, inflammatory joint diseases, etc.)
- Having cardiac arrhythmias
- Having a history of other metabolic bone diseases
- Having skin lesions at the electrode placement sites on the lower extremities
- Being older than 65 years
The study team makes the final eligibility decision.
Where it's taking place
- Bahçelievler, Istanbul, Turkey (Türkiye)
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18 years to 65 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Bahçelievler, Istanbul, Turkey (Türkiye). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.