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Compares treatment options for Hernia, Hiatal
Official title TLSA Versus TBSA Surgical Approach for Hiatal Hernia With Gastroesophageal Reflux Disease
ClinicalTrials.gov ID: NCT07252115
What this study is testing
- What it's testing
- Gastroesophageal reflux disease (GERD), characterized by pathological reflux of gastric contents, affects 10%-20% of the global population with Western predominance and escalating incidence over recent decades. Anatomical and functional abnormalities of the esophagogastric junction (EGJ) such as hiatal hernia (HH) is one of the major pathophysiological mechanisms.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 85
You may be able to join if
- Patients aged 18 to 85 years.
- Confirmed diagnosis of hiatal hernia (type I to IV).
- Diagnosis of refractory GERD, defined as persistent symptoms despite receiving 40 mg daily omeprazole for 8-12 weeks.
- GERD confirmed by either:
- Increased esophageal acid exposure time (AET) on 24-hour pH monitoring, and/or
You likely can't join if
- Presence of GERD without a hiatal hernia.
- Esophageal motility disorder.
- History of esophageal or other upper abdominal surgery.
See the full eligibility criteria
- Patients aged 18 to 85 years.
- Confirmed diagnosis of hiatal hernia (type I to IV).
- Diagnosis of refractory GERD, defined as persistent symptoms despite receiving 40 mg daily omeprazole for 8-12 weeks.
- GERD confirmed by either:
- Increased esophageal acid exposure time (AET) on 24-hour pH monitoring, and/or
- Endoscopic evidence of esophagitis.
- Hiatal hernia diagnosis verified by both abdominal CT and gastroscopy.
- Presence of GERD without a hiatal hernia.
- Esophageal motility disorder.
- History of esophageal or other upper abdominal surgery.
The study team makes the final eligibility decision.
Where it's taking place
- Beijing, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 85 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Beijing, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.