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New treatment option for Healthy Volunteers
Official title Neural Bases of Motivation
ClinicalTrials.gov ID: NCT07251816
What this study is testing
- What it's testing
- Effort-based decisions are essential in daily life but strongly impaired in apathy across various brain disorders. Now, significant research to unveil the neural causes of apathy is needed.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 40. Healthy volunteers may be eligible.
You may be able to join if
- Healthy volunteers aged between 18 and 40 years
- Participants without confounding factors such as neural alterations related to neurological pathology, whether neurodegenerative (e.g., Alzheimer...
- Participants affiliated with a compulsory social security scheme.
You likely can't join if
- Persons deprived of liberty by judicial or administrative decisions.
- Pregnant women, women in labor or breastfeeding women
- Persons admitted to a health or social institution for purposes other than research.
- Adults under legal protection measures (e.g., guardianship or curatorship).
- Participation in other treatment research with an ongoing non-inclusion period.
- Neurological or psychiatric disorders.
See the full eligibility criteria
- Healthy volunteers aged between 18 and 40 years
- Participants without confounding factors such as neural alterations related to neurological pathology, whether neurodegenerative (e.g., Alzheimer, Parkinson, Huntington, multiple sclerosis, amyotrophic lateral...
- Participants affiliated with a compulsory social security scheme.
- Persons deprived of liberty by judicial or administrative decisions.
- Pregnant women, women in labor or breastfeeding women
- Persons admitted to a health or social institution for purposes other than research.
- Adults under legal protection measures (e.g., guardianship or curatorship).
- Participation in other treatment research with an ongoing non-inclusion period.
- Neurological or psychiatric disorders.
- Use of tricyclic antidepressants (amitriptyline, clomipramine, imipramine, nortriptyline), neuroleptics (chlorpromazine, haloperidol, risperidone, olanzapine, quetiapine), or recreational drugs within the past 48 hours.
- Regular use of recreational drugs.
- Sleep deprivation (\< 5 hours regularly over the last 3 months)
- Left-handedness or ambidexterity.
- Physical injuries impacting motor tasks.
- Presence of metal implants in the head (excluding oral fillings).
- Presence of implanted medical devices (e.g., pacemaker).
- Presence of metallic injuries in the eyes.
- Claustrophobia.
- Piercings incompatible with MRI procedures.
- Contraindication to MRI
- Persons who refused to be informed of eventual medical anomalies discovered by the MRI
- Personal or family history (first-degree relatives) of epilepsy or seizures. Severe and/or frequent headaches (only for participants receiving transcranial magnetic stimulation, e.g preparatory experience 1 and...
- Baldness impeding electrode placement (only for participants receiving transcranial electrical stimulation and EEG measurements, e.g experiments 2, 3 and 4)
- Facial or ear pain and/or recent ear trauma (only for participants receiving transcutaneous vagal nerve stimulation, e.g experiment 5)
The study team makes the final eligibility decision.
Where it's taking place
- Bron, France
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 40 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Bron, France. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.