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New treatment option for Dental Caries
Official title Effect of MI Paste Plus™ on Streptococcus Mutans and White Spot Lesions in Fixed Orthodontics
ClinicalTrials.gov ID: NCT07244991
What this study is testing
- What it's testing
- Background This study is part of a doctoral research project at Universidad Cardenal Herrera CEU (Spain), directed by Prof. Santiago Arias de Luxán and conducted by doctoral candidate Shirli Kelmendi within the PhD program in Translational Medicine.
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 5 to 45. Healthy volunteers may be eligible.
You may be able to join if
- Age between 5 and 45 years.
- Indication for fixed orthodontic treatment, either with fixed auxiliary appliances (including orthopedic devices) or brackets with or without...
- General good health with no systemic diseases affecting oral health.
You likely can't join if
- Advanced white-spot lesions with untreated dentin involvement.
- Presence of active untreated dental caries at baseline.
- Antibiotic therapy within the previous two months.
- Previous diagnosis of molar-incisor hypomineralization (MIH).
- History of immunosuppression.
- Iron-deficiency anemia or other clinically relevant hematological disorders.
See the full eligibility criteria
- Age between 5 and 45 years.
- Indication for fixed orthodontic treatment, either with fixed auxiliary appliances (including orthopedic devices) or brackets with or without auxiliary components.
- General good health with no systemic diseases affecting oral health.
- Advanced white-spot lesions with untreated dentin involvement.
- Presence of active untreated dental caries at baseline.
- Antibiotic therapy within the previous two months.
- Previous diagnosis of molar-incisor hypomineralization (MIH).
- History of immunosuppression.
- Iron-deficiency anemia or other clinically relevant hematological disorders.
- Parafunctional habits such as lip sucking or finger sucking.
- Use of any type of dental prosthesis.
- Smoking or tobacco use.
- Documented allergy to nickel.
- Requirement for orthodontic treatment using removable appliances or clear aligners.
The study team makes the final eligibility decision.
Where it's taking place
- Tirana, Albania, Albania
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 5 years to 45 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Tirana, Albania, Albania. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.