BridgeMD
New treatment option for Alveolar Ridge Preservation
Official title Comparison of Demineralized and Mineralized Dentin Grafts in Ridge Preservation
ClinicalTrials.gov ID: NCT07242313
What this study is testing
What is Demineralized Allogeneic Dentin Graft?
Demineralized Allogeneic Dentin Graft is an investigational medicine, being studied as a potential treatment for alveolar ridge preservation.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This clinical investigation aims to assess how two different allogeneic dentin graft materials - one de-mineralized and the other mineralized - influence bone preservation following extraction of a single upper posterior tooth. A total of 45 patients will be randomly allocated into three equal groups: a socket-only spontaneous healing group (control), a de-mineralized dentin graft group, and a mineralized dentin graft group.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 60
You may be able to join if
- Adults aged 18 to 60 years.
- Medically healthy patients classified as ASA I.
- Presence of a single non-restorable tooth indicated for extraction in the posterior maxilla.
- Adequate oral hygiene, with plaque and bleeding indices both below 20%.
- Sufficient bone volume to allow socket preservation without requiring simultaneous augmentation.
You likely can't join if
- Smokers or tobacco users of any form.
- Presence of uncontrolled systemic diseases (e.g., uncontrolled diabetes).
- Conditions affecting bone metabolism (e.g., osteoporosis, long-term corticosteroid therapy).
- Pregnant or lactating women.
- History of radiotherapy in the head and neck region.
- Active infection or suppuration at the extraction site.
See the full eligibility criteria
- Adults aged 18 to 60 years.
- Medically healthy patients classified as ASA I.
- Presence of a single non-restorable tooth indicated for extraction in the posterior maxilla.
- Adequate oral hygiene, with plaque and bleeding indices both below 20%.
- Sufficient bone volume to allow socket preservation without requiring simultaneous augmentation.
- Patients willing to participate in the study and able to provide written informed consent.
- Ability to commit to follow-up visits for up to 6 months.
- Smokers or tobacco users of any form.
- Presence of uncontrolled systemic diseases (e.g., uncontrolled diabetes).
- Conditions affecting bone metabolism (e.g., osteoporosis, long-term corticosteroid therapy).
- Pregnant or lactating women.
- History of radiotherapy in the head and neck region.
- Active infection or suppuration at the extraction site.
- Immunocompromised patients or those on immunosuppressive therapy.
- Patients taking medications known to impair healing (e.g., bisphosphonates).
- Allergy or hypersensitivity to any study-related materials.
The study team makes the final eligibility decision.
Where it's taking place
- Kafr ash Shaykh, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 60 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Kafr ash Shaykh, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.