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New treatment option for Stroke
Official title Minocycline in Stroke Study at Maimonides
ClinicalTrials.gov ID: NCT07237048
What this study is testing
What is Minocycline 200mg?
Minocycline 200mg is an investigational medicine, given as an once-daily pill taken by mouth, being studied as a potential treatment for stroke.
Also referred to as Minocin, Minocycline hydrochloride.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The goal of this study is to determine if Minocycline, when added to standard care, can improve survival and functional outcomes in patients with moderate acute stroke (ischemic or hemorrhagic) aged 18 years and older. The main questions it aims to answer are: 1.
- Phase 3: a large, late-stage study
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- \ In order to be eligible to participate in this study, an individual must meet all of the following criteria:
- Age \>/=18
- NIHSS 5-20 \ National Institutes of Health Stroke Scale\
- Acute onset neurological deficit consistent with acute ischemic stroke or on imaging consistent with acute ischemia as defined by WHO \ (World Health...
- The onset of neurological symptoms less than 24 hours
You likely can't join if
- An individual who meets any of the following criteria is excluded from participation in this study:
- Clinically stroke is not suspected
- Allergic to the Tetracycline group of medications or Intolerance to Minocycline
- Pregnancy or suspected pregnancy or breastfeeding
- Previous history of intolerance to Minocycline
- Acute or chronic renal failure (stage III with GFR \ (Glomerular Filtration Rate) \ or Creatinine threshold)
See the full eligibility criteria
- \ In order to be eligible to participate in this study, an individual must meet all of the following criteria:
- Age \>/=18
- NIHSS 5-20 \ National Institutes of Health Stroke Scale\
- Acute onset neurological deficit consistent with acute ischemic stroke or on imaging consistent with acute ischemia as defined by WHO \ (World Health Organization) \ guidelines or acute onset of neurological deficits...
- The onset of neurological symptoms less than 24 hours
- An individual who meets any of the following criteria is excluded from participation in this study:
- Clinically stroke is not suspected
- Allergic to the Tetracycline group of medications or Intolerance to Minocycline
- Pregnancy or suspected pregnancy or breastfeeding
- Previous history of intolerance to Minocycline
- Acute or chronic renal failure (stage III with GFR \ (Glomerular Filtration Rate) \ or Creatinine threshold)
- Any patients with contraindications to undergo CT (Computed Tomography) / MRI (Magnetic Resonance Imaging)
- Life expectancy less than one year or severe co-morbidities or comfort measure only (CMO) on admission
- Pre-existing infectious disease requiring antibiotics
- Inability to tolerate enteral medications/feeds
- Patient/ family refusal
The study team makes the final eligibility decision.
Where it's taking place
- Brooklyn, New York, United States
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Brooklyn, New York, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.