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New treatment option for Aortic Stenosis
Official title Correlation Between an Impedance Cardiography Test for Decompensation and the Development of Left Ventricular Replacement Fibrosis
ClinicalTrials.gov ID: NCT07230964
What this study is testing
- What it's testing
- The purpose of this study is to evaluate the effectiveness of impedance cardiography (ICG), the HYPERGRAPH test, in detecting left ventricular decompensation in patients with aortic stenosis, compared to cardiac magnetic resonance (CMR) imaging findings. The study aims to obtain usable ICG test data on six patients with aortic stenosis who have recently undergone CMR scans with late gadolinium enhancement, and who do not have a history of myocardial infarction or cardiac amyloidosis.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Male or female at least 18 years of age.
- No prior history of myocardial infarction or cardiac amyloidosis.
- Recent CMR scan with late gadolinium enhancement or scheduled for CMR scan with late gadolinium enhancement.
- A history of:
- Moderate aortic stenosis and no replacement fibrosis OR Moderate aortic stenosis and symptoms who has replacement fibrosis OR Severe aortic stenosis...
You likely can't join if
- Under 18 years of age
- Pregnant or breastfeeding women
- Unable to consent
- Prisoners
- History of myocardial infarction
- History of cardiac amyloidosis
See the full eligibility criteria
- Male or female at least 18 years of age.
- No prior history of myocardial infarction or cardiac amyloidosis.
- Recent CMR scan with late gadolinium enhancement or scheduled for CMR scan with late gadolinium enhancement.
- A history of:
- Moderate aortic stenosis and no replacement fibrosis OR Moderate aortic stenosis and symptoms who has replacement fibrosis OR Severe aortic stenosis with replacement fibrosis prior to aortic valve replacement.
- Able to comprehend and provide informed consent in English.
- Participants must have intact, healthy skin at the electrode application sites.
- Under 18 years of age
- Pregnant or breastfeeding women
- Unable to consent
- Prisoners
- History of myocardial infarction
- History of cardiac amyloidosis
- Patients with any metal or implant such as IUD, braces, metal fragments implants in the eye, pacemakers (especially Minute Ventilation pacemakers with the MV function activated) defibrillators, or any other electronic...
- Claustrophobic or afraid or small places.
- Severe obesity (BMI \> 40) that impairs accurate ICG measurement due to difficulties in electrode placement or excessive impedance.
- Active skin conditions, such as rashes, open wound or significant skin sensitivity at the electrode placement sites.
The study team makes the final eligibility decision.
Where it's taking place
- Chicago, Illinois, United States
Compensation & support
A stipend or compensation may be offered.
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Chicago, Illinois, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.