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Tests treatment safety and results for Osteoarthritis Knee Pain
Official title Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain
ClinicalTrials.gov ID: NCT07226258
What this study is testing
What is SL1002?
SL1002 is an investigational medicine, given as an injectable medicine, being studied as a potential treatment for osteoarthritis knee pain.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- A Randomized, Double-Blind, Placebo-Controlled, Single Dose Study to Assess the Safety and Efficacy of SL1002 for the Treatment of Knee Pain in Patients with Osteoarthritis of the Knee.
- Phase 3: a large, late-stage study
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 40 and older
You may be able to join if
- includes:
- Male or female patients ≥ 40 years of age
- Body Mass Index (BMI) limits
- Chronic knee pain resulting from osteoarthritis
- Kellgren-Lawrence Grade 2 (mild) or Grade 3 (moderate)
You likely can't join if
- includes:
- Non-OA inflammatory arthritis
- Confounding elements
- Lower limb amputation.
- Specified alternate historic treatments
- Identified underlying physiologic or psychosocial conditions
See the full eligibility criteria
- includes:
- Male or female patients ≥ 40 years of age
- Body Mass Index (BMI) limits
- Chronic knee pain resulting from osteoarthritis
- Kellgren-Lawrence Grade 2 (mild) or Grade 3 (moderate)
- Baseline KOOS pain
- Patients taking baseline analgesics
- Diagnostic nerve block response
- Compliance with identified study requirements
- includes:
- Non-OA inflammatory arthritis
- Confounding elements
- Lower limb amputation.
- Specified alternate historic treatments
- Identified underlying physiologic or psychosocial conditions
- Patient Health Questionnaire
- Moderate to severe hepatic impairment
- Moderate to severe renal impairment
- Identifiable baseline medications
- Protocol compliance requirements
- Known allergies or hypersensitivity to identified agents
- Identified alcohol or drug abuse history
- Identified underlying physical exam findings: ECG abnormalities or vital sign abnormalities during study screening per investigator assessment
- Identified underlying abnormal laboratory results
The study team makes the final eligibility decision.
Where it's taking place
- Roseville, California, United States
- San Diego, California, United States
- Greenwood Village, Colorado, United States
- Washington D.C., District of Columbia, United States
- Coral Gables, Florida, United States
- Orlando, Florida, United States
- Winter Park, Florida, United States
- Rochester, Minnesota, United States
- Charlotte, North Carolina, United States
- Winston-Salem, North Carolina, United States
- Edmond, Oklahoma, United States
- Eugene, Oregon, United States
- Altoona, Pennsylvania, United States
- Sewickley, Pennsylvania, United States
- Charleston, South Carolina, United States
- Greenville, South Carolina, United States
- Bellaire, Texas, United States
- Corpus Christi, Texas, United States
- Tyler, Texas, United States
- Salt Lake City, Utah, United States
+ 1 more site(s).
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 40 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Roseville, California, United States; San Diego, California, United States; Greenwood Village, Colorado, United States; Washington D.C., District of Columbia, United States; Coral Gables, Florida, United States; Orlando, Florida, United States and 15 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.