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New treatment option for Multiple Sclerosis
Official title Prepare the Mind: Can Coaching in Goal-directed Behaviour Increase the Success of Cognitive Rehabilitation in People With MS?
ClinicalTrials.gov ID: NCT07225868
What this study is testing
- What it's testing
- People with Multiple Sclerosis (MS) often experience cognitive difficulties such as memory problems, concentration issues, and reduced processing speed. These symptoms can have a negative impact on daily functioning and overall quality of life.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- Confirmed relapsing remitting or secondary progressive MS diagnosis according to the McDonald 2017 criteria
- Expanded Disability Status Scale (EDSS) score \< 7
- Relapse free period ≥ 3 months
- Unchanged disease modifying therapy for ≥ 2 months at time of inclusion
- Age 18-65 years
You likely can't join if
- High conscientiousness, measured with a T score 65 or higher on the BFI-2 subscale for conscientiousness
- Current or prior brain trauma or neurological condition (other than MS)
- Psychiatric disorder that heavily impacts cognitive and/or daily functioning
- Medication intake and/or substance abuse that has an influence on cognitive functioning
- For Dutch subsample undergoing MRI: Contradiction for MRI
See the full eligibility criteria
- Confirmed relapsing remitting or secondary progressive MS diagnosis according to the McDonald 2017 criteria
- Expanded Disability Status Scale (EDSS) score \< 7
- Relapse free period ≥ 3 months
- Unchanged disease modifying therapy for ≥ 2 months at time of inclusion
- Age 18-65 years
- Language Dutch, English or German for each centre respectively
- High conscientiousness, measured with a T score 65 or higher on the BFI-2 subscale for conscientiousness
- Current or prior brain trauma or neurological condition (other than MS)
- Psychiatric disorder that heavily impacts cognitive and/or daily functioning
- Medication intake and/or substance abuse that has an influence on cognitive functioning
- For Dutch subsample undergoing MRI: Contradiction for MRI
The study team makes the final eligibility decision.
Where it's taking place
- Buffalo, New York, United States
- Leiden, Netherlands
- Rheinfelden, Switzerland
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Buffalo, New York, United States; Leiden, Netherlands; Rheinfelden, Switzerland. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.