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New treatment option for Spinal Tumors
Official title Liquid Biopsy Following BBB Disruption Using Barrier Disrupting Fields in Patients Undergoing Spine Surgery
ClinicalTrials.gov ID: NCT07224451
What this study is testing
- What it's testing
- Objective: To identify new central nervous system (CNS) biomarkers to be used for blood-derived liquid biopsy once the blood-brain barrier (BBB), specifically the blood-arachnoid barrier (BAB), has been transiently disrupted by BDF in patients undergoing spine surgery. Design: Single center (Sheba Medical Center), prospective, controlled.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Adult people over the age of 18
- Able to sign informed consent
- Candidates for intradural tumor resection spinal surgery with intraoperative neuromonitoring.
You likely can't join if
- Pacemakers, or other implanted electric medical devices
- Pregnant or lactating females
- Major medical, neurologic or psychiatric condition who are judged as unable to fully comply with the study
- History of skull fractures or previous brain surgery
- American Society of Anesthesiologists grade \>2
- Anticoagulants treatment
See the full eligibility criteria
- Adult people over the age of 18
- Able to sign informed consent
- Candidates for intradural tumor resection spinal surgery with intraoperative neuromonitoring.
- Pacemakers, or other implanted electric medical devices
- Pregnant or lactating females
- Major medical, neurologic or psychiatric condition who are judged as unable to fully comply with the study
- History of skull fractures or previous brain surgery
- American Society of Anesthesiologists grade \>2
- Anticoagulants treatment
- Damage to the dura resulting in CSF leak
- Patients with seizures/epilepsy
The study team makes the final eligibility decision.
Where it's taking place
- Ramat Gan, Israel
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Ramat Gan, Israel. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.