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New treatment option for T Cell Response to Dried Plum
Official title Prebiotics (Dried Plum) and Immune Function in Postmenopausal Women
ClinicalTrials.gov ID: NCT07222111
What this study is testing
- What it's testing
- Prior studies have shown that dietary supplementation with dried plums (also known as prunes) reduces bone loss in postmenopausal women. The purpose of this clinical trial is to understand how dried plums mediate their effects on bone.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 60 to 75, women only. Healthy volunteers may be eligible.
You may be able to join if
- women 60-75 years of age at the start of the study;
- 12 or more consecutive months without a menstrual period;
- willing to include dried plums in their daily diet and collect fecal samples at four time points;
- ambulatory without assistance;
- capacity to give informed consent.
You likely can't join if
- women who have been on medications known to alter bone or calcium metabolism (e.g., oral bisphosphonates, raloxifene, denosumab, intermittent...
- women who have been on hormone replacement therapy, steroids (i.e., glucocorticoids), biologics, or chronic NSAID within 3 months of starting the...
- women with a previous diagnosis of osteoporosis (i.e., BMD T-score or history of vertebral fracture or fragility fractures of hip, wrist, humerus...
- women who have undergone treatment for cancer within 12 months of starting the study
- women who have been taking prebiotic or probiotic supplements or natural products that have estrogen-like effects in the past 3 months
- women who smoke, have a BMI \>40 kg/m2 or \ 2 alcoholic drinks per day
See the full eligibility criteria
- women 60-75 years of age at the start of the study;
- 12 or more consecutive months without a menstrual period;
- willing to include dried plums in their daily diet and collect fecal samples at four time points;
- ambulatory without assistance;
- capacity to give informed consent.
- women who have been on medications known to alter bone or calcium metabolism (e.g., oral bisphosphonates, raloxifene, denosumab, intermittent parathyroid hormone, growth hormone) within 12 months of starting the study...
- women who have been on hormone replacement therapy, steroids (i.e., glucocorticoids), biologics, or chronic NSAID within 3 months of starting the study.
- women with a previous diagnosis of osteoporosis (i.e., BMD T-score or history of vertebral fracture or fragility fractures of hip, wrist, humerus after the age of 50 yr) or other metabolic bone disease (e.g...
- women who have undergone treatment for cancer within 12 months of starting the study
- women who have been taking prebiotic or probiotic supplements or natural products that have estrogen-like effects in the past 3 months
- women who smoke, have a BMI \>40 kg/m2 or \ 2 alcoholic drinks per day
- women who regularly consume dried plums or prune juice (\>1 serving weekly).
The study team makes the final eligibility decision.
Where it's taking place
- Indianapolis, Indiana, United States
Compensation & support
Some study costs may be covered.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 60 years to 75 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Indianapolis, Indiana, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.