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New treatment option for Parkinsons Disease (PD)
Official title Nutritional Intervention for Constipation Symptoms in Patients With Parkinson's Disease
ClinicalTrials.gov ID: NCT07213856
What this study is testing
- What it's testing
- The goal of this clinical trial is to evaluate whether a dietitian-guided nutritional intervention can improve constipation symptoms in people with Parkinson's disease (PD). The main questions it aims to answer are: Can a dietitian-guided nutritional intervention increase the number of weekly bowel movements in individuals with PD and functional constipation?
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Adults with a previous diagnosis of Parkinson's disease
- On a stable dose of levodopa for at least 3 months
- Diagnosis of Functional Constipation by the Rome IV protocol
You likely can't join if
- Diagnosis of atypical or secondary parkinsonism
- Hoehn and Yahr stage greater than 2
- Presence of severe neurological or psychiatric disorders that impair the ability to participate in study procedures
- Previous diagnosis of dementia
- Presence of comorbidities such as active cancer, chronic obstructive pulmonary disease (COPD), heart failure, and/or chronic kidney disease
- History of gastrointestinal cancers, inflammatory bowel diseases, or surgeries involving the gastrointestinal tract
See the full eligibility criteria
- Adults with a previous diagnosis of Parkinson's disease
- On a stable dose of levodopa for at least 3 months
- Diagnosis of Functional Constipation by the Rome IV protocol
- Diagnosis of atypical or secondary parkinsonism
- Hoehn and Yahr stage greater than 2
- Presence of severe neurological or psychiatric disorders that impair the ability to participate in study procedures
- Previous diagnosis of dementia
- Presence of comorbidities such as active cancer, chronic obstructive pulmonary disease (COPD), heart failure, and/or chronic kidney disease
- History of gastrointestinal cancers, inflammatory bowel diseases, or surgeries involving the gastrointestinal tract
- Constipation secondary to clinical conditions such as hypothyroidism or diabetes mellitus
- Use of opioids
- Use of probiotics or antibiotics in the past 8 weeks
- Continuous use of laxatives in the past 8 weeks
- Presence of severe dysphagia according to the Functional Oral Intake Scale (FOIS)
- Individuals receiving enteral or parenteral nutrition
- Individuals under nutritional follow-up in the past 3 months
The study team makes the final eligibility decision.
Where it's taking place
- Porto Alegre, Rio Grande do Sul, Brazil
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Porto Alegre, Rio Grande do Sul, Brazil. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.