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New treatment option for Down Syndrome (DS)
Official title Effects of Chronic Creatine and Beta-Hydroxy-Beta-Methylbutyrate Supplementation on Oxidative Stress, Inflammation, Muscle Strength, and Body Composition in Individuals With Down Syndrome
ClinicalTrials.gov ID: NCT07213063
What this study is testing
- What it's testing
- Purpose: This study will test whether 8 weeks of creatine and HMB supplementation can improve muscle strength, body composition, balance, and overall health in people with Down syndrome. Participants will also receive nutrition tips during the study.
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Diagnosis: Medical confirmation of Down syndrome (trisomy of chromosome 21).
- Physical capacity: Ability to perform basic physical tests (e.g., standing up from a chair or walking without assistance).
- Informed consent: Informed consent will be obtained from both the participant and their legal representative, in compliance with current legislation...
You likely can't join if
- Chronic kidney disease: Diagnosis of chronic kidney disease.
- Severe motor limitations: Inability to perform the required physical tests (e.g., paralysis or mobility impairments preventing the execution of...
- Participation in other studies: Participation in another nutritional or supplementation intervention study within the last 6 months.
- Allergies or intolerances: Known allergy to creatine or to components of the placebo (inulin).
The study team makes the final eligibility decision.
Where it's taking place
- Burgos, Burgos, Spain
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Burgos, Burgos, Spain. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.