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Official title Evaluation of Regenerative Endodontic Treatment for Immature Teeth
ClinicalTrials.gov ID: NCT07210359
What this study is testing
- What it's testing
- The goal of this clinical trial is to evaluate if regenerative endodontic treatment using two different forms of demineralized dentin matrix (DDM) can effectively treat immature permanent single-rooted teeth compared to treatment using RetroMTA in patients aged 9 to 15 years. The main questions it aims to answer are: Does the use of DDM improve clinical and radiographic outcomes such as root length, dentinal wall thickness, and apex closure?
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 9 to 15. Healthy volunteers may be eligible.
You may be able to join if
- Systemically healthy patients (i.e., free of any systemic diseases).
- Patients presenting with immature permanent single-rooted teeth.
- Age: 9 -15 years.
- Teeth diagnosed as either vital (asymptomatic irreversible pulpitis or symptomatic irreversible pulpitis and the bleeding didn't stop after 5 minutes...
You likely can't join if
- Patients who are allergic to any drugs used in this study or with systemic illness
- Teeth that are grossly decayed or fractured and require post and core as final restorations
- Presence of periodontal pockets greater than 4 mm.
- Radiographical evidence of apical foramen less than 1 mm.
- Presence of periapical radiolucency exceeding 10 mm.
- Presence of external or internal root resorption.
See the full eligibility criteria
- Systemically healthy patients (i.e., free of any systemic diseases).
- Patients presenting with immature permanent single-rooted teeth.
- Age: 9 -15 years.
- Teeth diagnosed as either vital (asymptomatic irreversible pulpitis or symptomatic irreversible pulpitis and the bleeding didn't stop after 5 minutes application of hemostatic agent) or non-vital pulp.
- Patients who are allergic to any drugs used in this study or with systemic illness
- Teeth that are grossly decayed or fractured and require post and core as final restorations
- Presence of periodontal pockets greater than 4 mm.
- Radiographical evidence of apical foramen less than 1 mm.
- Presence of periapical radiolucency exceeding 10 mm.
- Presence of external or internal root resorption.
- Patients with a history of major surgeries like cardiac, kidney transplantation, haemodialysis.
The study team makes the final eligibility decision.
Where it's taking place
- Kafr ash Shaykh, Kafr Elsheikh, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 9 years to 15 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Kafr ash Shaykh, Kafr Elsheikh, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.