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New treatment option for Immunosuppression
Official title Fibroscan to Guide Post Transplant Immunosuppression Minimization
ClinicalTrials.gov ID: NCT07206277
What this study is testing
- What it's testing
- Following Liver transplantation, recipients remain on life long immunosuppression. Prolonged exposure to immunosuppression is associated with side effects and complications including kidney dysfunction, diabetes, heart disease and cancer risk.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- 2 years or more post-liver transplant
- 18 years or older
You likely can't join if
- diagnosis of either acute or chronic rejection in the past 12 months
- abnormal liver enzymes (ALT \> 50; bilirubin \> 19 umol/L)
- transplant for autoimmune liver disease (autoimmune hepatitis, primary sclerosing cholangitis, and primary biliary cholangitis)
- presence of HCV RNA
- presence of HBV DNA
- presence of class II donor specific antibodies (DSA; pre-existing or de novo)
See the full eligibility criteria
- 2 years or more post-liver transplant
- 18 years or older
- diagnosis of either acute or chronic rejection in the past 12 months
- abnormal liver enzymes (ALT \> 50; bilirubin \> 19 umol/L)
- transplant for autoimmune liver disease (autoimmune hepatitis, primary sclerosing cholangitis, and primary biliary cholangitis)
- presence of HCV RNA
- presence of HBV DNA
- presence of class II donor specific antibodies (DSA; pre-existing or de novo)
- beyond 6 years of transplantation
- presence of ascites, decompensated heart failure, biliary obstruction, CKD (bl eGFR 30 ml/min/1.73m2 or less), re-transplantation, or multi-visceral transplant.
The study team makes the final eligibility decision.
Where it's taking place
- Edmonton, Alberta, Canada
Compensation & support
A stipend or compensation may be offered.
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Edmonton, Alberta, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.