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New treatment option for CAD
Official title Adding Lidocaine to Custodiol Mixture
ClinicalTrials.gov ID: NCT07205757
What this study is testing
What is Lidocaine Hydrochloride?
Lidocaine Hydrochloride is an investigational medicine, given as an once-daily infusion into a vein, being studied as a potential treatment for cad.
Also referred to as Xylocaine.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The Bretschneider solution, also known as Custodiol, has been widely used in open-heart surgery requiring cardiopulmonary bypass (CPB) since its introduction in 1970. Custodiol is widely favored by cardiac surgeons, being administered as a single dose, and is supposed to offer myocardial protection for up to three hours, permitting an uninterrupted surgical time, especially for intricate procedures The literature continues to debate the superiority of custodial and other cardioplegic solutions, such as the Del Nido and St.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- patients scheduled for elective Coronary artery bypass grafting surgery
You likely can't join if
- Emergency or Redo surgery.
- Baseline rhythm other than sinus rhythm
- Any degree of heart block, bundle branch block or hemiblock
- Known allergy to lidocaine.
- Chronic kidney disease.
- Hepatic impairment.
See the full eligibility criteria
- patients scheduled for elective Coronary artery bypass grafting surgery
- Emergency or Redo surgery.
- Baseline rhythm other than sinus rhythm
- Any degree of heart block, bundle branch block or hemiblock
- Known allergy to lidocaine.
- Chronic kidney disease.
- Hepatic impairment.
- Severe psychiatric illness.
The study team makes the final eligibility decision.
Where it's taking place
- Al Fayyum, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Al Fayyum, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.