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Official title Assessment of Respiratory Drive and Inspiratory Effort Across Pressure Support Levels in Patients After Major Abdominal Surgery
ClinicalTrials.gov ID: NCT07199881
What this study is testing
- What it's testing
- This physiological observational study will assess respiratory drive and inspiratory effort across varying levels of pressure support ventilation (PSV) in adult surgical ICU (SICU) patients after major abdominal surgery. By using non-invasive bedside indices (airway occlusion pressure at 100 ms after the onset of inspiration [P0.1], maximum negative occlusion pressure [Pocc], and pressure muscle index [PMI]), we aim to quantify how patients adapt to changes in ventilatory support and determine patterns of under- and over-assistance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Adult patients (≥18 years) admitted to the surgical ICU
- Recent major abdominal surgery (intra-peritoneal operation without primary thoracic involvement, including luminal resection and/or resection of a...
- Receiving invasive mechanical ventilation in pressure support ventilation (PSV) mode at the time of enrollment
- Duration of invasive mechanical ventilation \>48 hours
- Clinically stable, with no plan for extubation within 6 hours of study enrollment, defined by all of the following: Respiratory rate \<35...
You likely can't join if
- Known neuromuscular disease affecting respiratory muscle function
- Hemodynamic instability requiring escalation of vasopressor support
- Severe hypoxemic respiratory failure requiring Positive End-Expiratory Pressure (PEEP) \>10 cmH₂O or FiO₂ \>60%
- Deep sedation (Richmond Agitation-Sedation Scale [RASS] score \< -3) or ongoing neuromuscular blockade
- History of chronic obstructive pulmonary disease (COPD) or other obstructive lung disease
The study team makes the final eligibility decision.
Where it's taking place
- Bangkok, Bangkoknoi, Thailand
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Bangkok, Bangkoknoi, Thailand. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.