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New treatment option for Advanced Solid Tumors
Official title A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies
ClinicalTrials.gov ID: NCT07197554
What this study is testing
What is ST-01156?
ST-01156 is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for advanced solid tumors.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- A Phase 1/1B Study of ST-01156 in Patients with Advanced Solid Malignancies
- Phase 1: an early, usually small safety study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 16 and older
You may be able to join if
- Age ≥ 18 years on the day of signing the consent form, except for adolescents with Ewing Sarcoma or other malignancies for which there is a...
- Has a metastatic or locally advanced and unresectable solid tumor.
- Has at least 1 measurable lesion or evaluable disease per RECIST v1.1.
- Has an ECOG performance status ≤ 2 at screening.
- Has adequate organ function as defined in the protocol.
You likely can't join if
- Has received prior radiotherapy within 2 weeks of treatment.
- Has known active CNS metastases and/or carcinomatous meningitis. Participants with previously treated brain metastases may participate, provided they...
- Has received treatment with any local or systemic anticancer therapy or investigational anticancer agent within 14 days or 5 half-lives, whichever is...
- Had major surgery within 28 days before study therapy administration
- Has toxicities from previous anticancer therapies that have not resolved to baseline levels, with the exception of alopecia and peripheral neuropathy.
- Has previously received a RBM39 inhibitor/degrader.
The study team makes the final eligibility decision.
Where it's taking place
- Duarte, California, United States
- Newport Beach, California, United States
- Boston, Massachusetts, United States
- New York, New York, United States
- Houston, Texas, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 16 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Duarte, California, United States; Newport Beach, California, United States; Boston, Massachusetts, United States; New York, New York, United States; Houston, Texas, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.