BridgeMD
New treatment option for Acute Hypoxemic Respiratory Failure
Official title IntHyx : Intubation Strategies for Patients With Acute Hypoxemic Respiratory Failure
ClinicalTrials.gov ID: NCT07189078
What this study is testing
- What it's testing
- Acute hypoxemic respiratory failure requires endotracheal intubation and invasive mechanical ventilation in approximately 30-40% of cases, due to severe hypoxemia and/or clinical signs of acute respiratory distress. The primary objectives of invasive mechanical ventilation are to reduce respiratory effort and improve oxygenation.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Adult patient
- Patient admitted to intensive care less than 24 hours ago
- Acute respiratory failure with hypoxemia defined by either:
- Oxygen therapy ≥ 10 L/min via high-concentration mask required for SpO2 ≥ 92%
- High-flow oxygen therapy with FiO2 ≥ 50% required for SpO2 ≥ 92%
You likely can't join if
- Acute hypercapnic respiratory failure (defined by PaCO2 \> 45 mmHg)
- Cardiogenic pulmonary edema
- Exacerbation of chronic respiratory disease
- Respiratory failure requiring long-term oxygen therapy
- Neuromuscular disease
- Glasgow Coma Scale score ≤ 12
See the full eligibility criteria
- Adult patient
- Patient admitted to intensive care less than 24 hours ago
- Acute respiratory failure with hypoxemia defined by either:
- Oxygen therapy ≥ 10 L/min via high-concentration mask required for SpO2 ≥ 92%
- High-flow oxygen therapy with FiO2 ≥ 50% required for SpO2 ≥ 92%
- Informed consent of the patient or a trusted relative (when the patient is unable to give consent)
- Acute hypercapnic respiratory failure (defined by PaCO2 \> 45 mmHg)
- Cardiogenic pulmonary edema
- Exacerbation of chronic respiratory disease
- Respiratory failure requiring long-term oxygen therapy
- Neuromuscular disease
- Glasgow Coma Scale score ≤ 12
- Decision to intubate immediately
- Invasive mechanical ventilation within the previous 7 days
- Treatment limitation decisions for intubation
- Person deprived of liberty by judicial or administrative decision : Person undergoing compulsory psychiatric care, person subject to legal protection measures, Pregnant, breastfeeding, or parturient patient
The study team makes the final eligibility decision.
Where it's taking place
- Angers, France
- Le Mans, France
- Nantes, France
- Orléans, France
- Paris, France
- Pointe à Pitre, France
- Rennes, France
- Tours, France
- Vannes, France
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Angers, France; Le Mans, France; Nantes, France; Orléans, France; Paris, France; Pointe à Pitre, France and 3 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.