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Compares treatment options for SCD
Official title Efficacy of Liberal Versus Restricted IV Fluid Approach in the Management of Sickle Cell Vaso-Occlusive Crisis
ClinicalTrials.gov ID: NCT07188766
What this study is testing
What is Sodium Chloride (NaCl) 0.9 %?
Sodium Chloride (NaCl) 0.9 % is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for scd.
Also referred to as Restricted.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Sickle cell disease (SCD) is a prevalent inherited blood disorder characterized by vaso-occlusive crises (VOCs), which lead to severe pain and complications. Despite hydration being a cornerstone of VOC management, the optimal fluid strategy remains uncertain.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 60
You may be able to join if
- Patients \>18 years old with a confirmed diagnosis of SCD.
- Presenting with a VOC.
- NPRS \>5
- Willingness to participate and provide informed consent.
You likely can't join if
- Patient requiring specialized IVF management as per the treating physician discretion.
- Patients with congestive heart failure, and /or acute or chronic symptomatic systolic heart failure
- Patients with ESRD on chronic dialysis
- Patients with signs of shock (low SBP \<100 or MAP \< 65) and signs of hypo perfusion
- Known or suspected pregnancy
- Previously enrolled in this trial within the last 30 days
See the full eligibility criteria
- Patients \>18 years old with a confirmed diagnosis of SCD.
- Presenting with a VOC.
- NPRS \>5
- Willingness to participate and provide informed consent.
- Patient requiring specialized IVF management as per the treating physician discretion.
- Patients with congestive heart failure, and /or acute or chronic symptomatic systolic heart failure
- Patients with ESRD on chronic dialysis
- Patients with signs of shock (low SBP \<100 or MAP \< 65) and signs of hypo perfusion
- Known or suspected pregnancy
- Previously enrolled in this trial within the last 30 days
- Enrolled in another trial study that interfered with fluid management
- Unable to obtain IV access.
The study team makes the final eligibility decision.
Where it's taking place
- Dammam, Eastern Province, Saudi Arabia
- Riyadh, Saudi Arabia
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 60 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Dammam, Eastern Province, Saudi Arabia; Riyadh, Saudi Arabia. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.