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New treatment option for Anterior Cruciate Ligament
Official title Clinical Outcome of Intra Articular Injection of Autologous Platelet Rich Plasma in Anterior Cruciate Ligament Injury.
ClinicalTrials.gov ID: NCT07185802
What this study is testing
What is PRP injection?
PRP injection is an investigational medicine, given as an injectable medicine, being studied as a potential treatment for anterior cruciate ligament.
Also referred to as PRP group.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This clinical trial will evaluate the effectiveness of platelet-rich plasma (PRP) injections for patients with anterior cruciate ligament (ACL) injury. ACL injuries commonly cause knee instability, pain, and reduced function, and rehabilitation alone may not fully restore recovery in all patients.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 50
You may be able to join if
- Patients of both sexes who are older than 18 years and younger than 50 years
- 3 or Less than 3-months history of knee injuries
- ACL injury MRI Grade 1 (Low) and medium Grade 2 (Medium) grade
- ACL injury associated with Grade 1 or 2 Posterior cruciate ligament (PCL) tear and/or Grade 1 or 2 meniscal tear
- The Complete Blood Count (CBC) report shows a hemoglobin \> 10gm/dl and platelet count \>150,000/microliter prior to the procedure
You likely can't join if
- Patients who have had intra articular corticosteroid injections in the index knee during the last 12 weeks
- Patients who are taking systemic steroid
- Patients who are younger than 18 and older than 50 years
- Those with a history of platelet disorders or on the therapeutic anticoagulant or anti platelet drugs
- Hemoglobin below 10 gm/dl
- Platelet count \<150000/microliter
See the full eligibility criteria
- Patients of both sexes who are older than 18 years and younger than 50 years
- 3 or Less than 3-months history of knee injuries
- ACL injury MRI Grade 1 (Low) and medium Grade 2 (Medium) grade
- ACL injury associated with Grade 1 or 2 Posterior cruciate ligament (PCL) tear and/or Grade 1 or 2 meniscal tear
- The Complete Blood Count (CBC) report shows a hemoglobin \> 10gm/dl and platelet count \>150,000/microliter prior to the procedure
- Capable of comprehending informed consent
- Patients who have had intra articular corticosteroid injections in the index knee during the last 12 weeks
- Patients who are taking systemic steroid
- Patients who are younger than 18 and older than 50 years
- Those with a history of platelet disorders or on the therapeutic anticoagulant or anti platelet drugs
- Hemoglobin below 10 gm/dl
- Platelet count \<150000/microliter
- Complete tear of both bundles on MRI
- Grade 3 or more PCL and meniscal tear on MRI
- Previous or concurrent ligament reconstruction in the index knee joint.
- Connective tissue disorders like Marfan Syndrome, Ehler-Danlos Syndrome etc.
- Any inflammatory disease like Rheumatoid Arthritis, spondyloarthritis, gout, pseudogout etc involving the knee joint.
The study team makes the final eligibility decision.
Where it's taking place
- Dhaka, Bangladesh
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 50 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Dhaka, Bangladesh. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.