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Compares treatment options for Dental Caries
Official title SDF vs Fluoride Varnish for Streptococcus Mutans Reduction in Children
ClinicalTrials.gov ID: NCT07181967
What this study is testing
What is Sodium Fluoride Varnish (5%)?
Sodium Fluoride Varnish (5%) is an investigational medicine, given as a treatment applied to the skin, being studied as a potential treatment for dental caries.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This randomized split-mouth clinical trial will compare the effectiveness of 38% silver diamine fluoride (SDF) versus 5% sodium fluoride varnish (FV) in reducing salivary Streptococcus mutans levels in children with bilateral caries. Each participant will receive SDF on one side of the mouth and FV on the contralateral side.
- Time commitment: about 3 months
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 3 to 8
You may be able to join if
- Age 3-8 years; cooperative (Frankl ≥2).
- ≥2 contralateral primary molars with active dentin caries (ICDAS 3-5) of comparable severity.
- Parent/guardian consent; child assent when appropriate.
You likely can't join if
- Silver allergy; ulcerative gingivitis/stomatitis.
- Systemic antibiotics within 4 weeks.
- Fixed appliances interfering with plaque assessment.
- Conditions precluding safe participation per clinician judgment.
The study team makes the final eligibility decision.
Where it's taking place
- Asyut, Asyut Governorate, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 3 months per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 3 years to 8 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Asyut, Asyut Governorate, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.