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Compares treatment options for Spine Disease
Official title Comparison of Perineural Dexamethasone Versus Dexmedetomidine as Adjuvants to Erector Spinae Plane Block in Lumbar Spine Surgery: A Randomized, Double-blind, Controlled Trial
ClinicalTrials.gov ID: NCT07180940
What this study is testing
What is 0.9%NaCl?
0.9%NaCl is an investigational medicine, being studied as a potential treatment for spine disease.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This clinical study aims to determine which of two medications-dexamethasone or dexmedetomidine-works better and is safer when used together with a local anesthetic (ropivacaine) in a type of nerve block called the erector spinae plane block (ESPB). This block helps reduce pain after lumbar spine surgery.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Adults aged 18 to N/A (no limit)
- Scheduled for elective lumbar spine surgery (e.g., decompression or fusion) via posterior approach
- American Society of Anesthesiologists (ASA) physical status I-III
- Body weight ≥ 50 kg
- Ability to provide written informed consent
You likely can't join if
- Known allergy or contraindication to ropivacaine, dexamethasone, or dexmedetomidine
- Infection at or near the site of block placement
- Coagulation disorders or current use of anticoagulant therapy (not discontinued per guidelines)
- Chronic opioid use or opioid dependence
- Neurological or psychiatric disorders interfering with pain assessment
- Diabetes mellitus with poorly controlled glycemia (e.g., HbA1c \> 8%)
See the full eligibility criteria
- Adults aged 18 to N/A (no limit)
- Scheduled for elective lumbar spine surgery (e.g., decompression or fusion) via posterior approach
- American Society of Anesthesiologists (ASA) physical status I-III
- Body weight ≥ 50 kg
- Ability to provide written informed consent
- Expected postoperative hospitalization of at least 48 hours
- Known allergy or contraindication to ropivacaine, dexamethasone, or dexmedetomidine
- Infection at or near the site of block placement
- Coagulation disorders or current use of anticoagulant therapy (not discontinued per guidelines)
- Chronic opioid use or opioid dependence
- Neurological or psychiatric disorders interfering with pain assessment
- Diabetes mellitus with poorly controlled glycemia (e.g., HbA1c \> 8%)
- Severe hepatic or renal dysfunction
- Body mass index (BMI) \> 40 kg/m²
- Pregnancy or breastfeeding
- Refusal or inability to cooperate with the study protocol
The study team makes the final eligibility decision.
Where it's taking place
- Poznan, Poland
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Poznan, Poland. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.