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New treatment option for Muscular Atrophy
Official title Human Skeletal Muscle Response to 5 Days of Bedrest in Young Adults
ClinicalTrials.gov ID: NCT07178353
What this study is testing
- What it's testing
- The goal of this intervention trial is to characterize skeletal muscle atrophy in healthy, young adults during short term bedrest. The main questions it aims to answer are: How much do skeletal muscle volume, strength, and fatigue resistance decline during bedrest?
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 30. Healthy volunteers may be eligible.
You may be able to join if
- Males and females 18-30 years
- BMI between 18.5-28 kg/m2
- Weight stable (within ±2kg for 6 months)
- Generally healthy as assessed by medical and physical activity questionnaires
- recreationally active
You likely can't join if
- a BMI \ 28 kg/m2
- the use of insulin to control blood glucose levels
- a history of any cardiovascular, respiratory, metabolic diseases, neuromuscular or bone-wasting diseases
- the use of any medication that may affect muscle protein turnover (e.g. androgen or anabolic hormone therapy, chemotherapy)
- a (family) history of thrombosis, platelet or coagulation disorders, or antiplatelet therapy and the use of anticoagulant medications
- the presence of any unremoved, or partially removed metals underneath the skin
See the full eligibility criteria
- Males and females 18-30 years
- BMI between 18.5-28 kg/m2
- Weight stable (within ±2kg for 6 months)
- Generally healthy as assessed by medical and physical activity questionnaires
- recreationally active
- a BMI \ 28 kg/m2
- the use of insulin to control blood glucose levels
- a history of any cardiovascular, respiratory, metabolic diseases, neuromuscular or bone-wasting diseases
- the use of any medication that may affect muscle protein turnover (e.g. androgen or anabolic hormone therapy, chemotherapy)
- a (family) history of thrombosis, platelet or coagulation disorders, or antiplatelet therapy and the use of anticoagulant medications
- the presence of any unremoved, or partially removed metals underneath the skin
- a history of head or eye injury involving metal fragments
- have some type of implanted electrical device (such as a cardiac pacemaker or neurostimulator)
- have implanted metal objects as a result of surgery, such as artificial joints, aneurysm clips, metal staples
- are, or may be, pregnant
- are wearing metal braces on their teeth.
The study team makes the final eligibility decision.
Where it's taking place
- Kingston, Ontario, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 30 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Kingston, Ontario, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.