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New treatment option for Autoimmune Cytopenia
Official title A Study of CM336 in Patients With Relapsed or Refractory Autoimmune Cytopenia
ClinicalTrials.gov ID: NCT07175493
What this study is testing
What is CM336 Injection?
CM336 Injection is an investigational medicine, given as an injection under the skin, being studied as a potential treatment for autoimmune cytopenia.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- To evaluate the efficacy and safety of CM336 (BCMA/CD3 Bispecific Antibody) in the treatment of patients with relapsed or refractory autoimmune cytopenia
- Phase 2: a mid-size study of how well it works
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Voluntary provision of written informed consent and ability to comply with protocol requirements.
- Age ≥18 years, male or female.
- Eastern Cooperative Oncology Group (ECOG) Performance Status of 0 to 2.
- Confirmed diagnosis of immune thrombocytopenia (ITP), warm autoimmune hemolytic anemia (wAIHA), cold agglutinin disease (CAD), mixed autoimmune...
- Relapsed or refractory autoimmune hemolytic anemia.
You likely can't join if
- Secondary ITP or AIHA caused by any reason. people with positive autoimmune antibodies but without a clear diagnosis of any other autoimmune diseases...
- Other types of AIHA or other types of cytopenia
- History of critical diseases that, in the opinion of the investigator, may pose a risk to the safety of people or whose exacerbation during the study...
- Received any treatment of anti-B Cell Maturation Antigen(BCMA) antibody.
- Evaluated unsuitable to participant in this study by investigator.
The study team makes the final eligibility decision.
Where it's taking place
- Zhengzhou, Henan, China
- Changzhi, Shanxi, China
- Tianjin, Tianjin Municipality, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Zhengzhou, Henan, China; Changzhi, Shanxi, China; Tianjin, Tianjin Municipality, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.